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Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility.
Wang F, Huang S, Gao R, Zhou Y, Lai C, Li Z, Xian W, Qian X, Li Z, Huang Y, Tang Q, Liu P, Chen R, Liu R, Li X, Tong X, Zhou X, Bai Y, Duan G, Zhang T, Xu X, Wang J, Yang H, Liu S, He Q, Jin X, Liu L. Wang F, et al. Among authors: zhang t. Cell Discov. 2020 Nov 10;6(1):83. doi: 10.1038/s41421-020-00231-4. Cell Discov. 2020. PMID: 33298875 Free PMC article.
An integrated tool to study MHC region: accurate SNV detection and HLA genes typing in human MHC region using targeted high-throughput sequencing.
Cao H, Wu J, Wang Y, Jiang H, Zhang T, Liu X, Xu Y, Liang D, Gao P, Sun Y, Gifford B, D'Ascenzo M, Liu X, Tellier LC, Yang F, Tong X, Chen D, Zheng J, Li W, Richmond T, Xu X, Wang J, Li Y. Cao H, et al. Among authors: zhang t. PLoS One. 2013 Jul 24;8(7):e69388. doi: 10.1371/journal.pone.0069388. Print 2013. PLoS One. 2013. PMID: 23894464 Free PMC article.
Deep sequencing of the MHC region in the Chinese population contributes to studies of complex disease.
Zhou F, Cao H, Zuo X, Zhang T, Zhang X, Liu X, Xu R, Chen G, Zhang Y, Zheng X, Jin X, Gao J, Mei J, Sheng Y, Li Q, Liang B, Shen J, Shen C, Jiang H, Zhu C, Fan X, Xu F, Yue M, Yin X, Ye C, Zhang C, Liu X, Yu L, Wu J, Chen M, Zhuang X, Tang L, Shao H, Wu L, Li J, Xu Y, Zhang Y, Zhao S, Wang Y, Li G, Xu H, Zeng L, Wang J, Bai M, Chen Y, Chen W, Kang T, Wu Y, Xu X, Zhu Z, Cui Y, Wang Z, Yang C, Wang P, Xiang L, Chen X, Zhang A, Gao X, Zhang F, Xu J, Zheng M, Zheng J, Zhang J, Yu X, Li Y, Yang S, Yang H, Wang J, Liu J, Hammarström L, Sun L, Wang J, Zhang X. Zhou F, et al. Among authors: zhang c, zhang a, zhang f, zhang t, zhang j, zhang x, zhang y. Nat Genet. 2016 Jul;48(7):740-6. doi: 10.1038/ng.3576. Epub 2016 May 23. Nat Genet. 2016. PMID: 27213287
Genome-wide characteristics of de novo mutations in autism.
Yuen RK, Merico D, Cao H, Pellecchia G, Alipanahi B, Thiruvahindrapuram B, Tong X, Sun Y, Cao D, Zhang T, Wu X, Jin X, Zhou Z, Liu X, Nalpathamkalam T, Walker S, Howe JL, Wang Z, MacDonald JR, Chan A, D'Abate L, Deneault E, Siu MT, Tammimies K, Uddin M, Zarrei M, Wang M, Li Y, Wang J, Wang J, Yang H, Bookman M, Bingham J, Gross SS, Loy D, Pletcher M, Marshall CR, Anagnostou E, Zwaigenbaum L, Weksberg R, Fernandez BA, Roberts W, Szatmari P, Glazer D, Frey BJ, Ring RH, Xu X, Scherer SW. Yuen RK, et al. Among authors: zhang t. NPJ Genom Med. 2016 Aug 3;1:160271-1602710. doi: 10.1038/npjgenmed.2016.27. NPJ Genom Med. 2016. PMID: 27525107 Free PMC article.
Sequencing of the MHC region defines HLA-DQA1 as the major genetic risk for seropositive rheumatoid arthritis in Han Chinese population.
Guo J, Zhang T, Cao H, Li X, Liang H, Liu M, Zou Y, Zhang Y, Wang Y, Sun X, Hu F, Du Y, Mo X, Liu X, Yang Y, Yang H, Wu X, Zhang X, Jia H, Jiang H, Hou Y, Liu X, Su Y, Zhang M, Yang H, Wang J, Sun L, Liu L, Padyukov L, Lai L, Yamamoto K, Zhang X, Klareskog L, Xu X, Li Z. Guo J, et al. Among authors: zhang m, zhang t, zhang x, zhang y. Ann Rheum Dis. 2019 Jun;78(6):773-780. doi: 10.1136/annrheumdis-2018-214725. Epub 2019 Apr 1. Ann Rheum Dis. 2019. PMID: 30936065
Metagenome-wide association of gut microbiome features for schizophrenia.
Zhu F, Ju Y, Wang W, Wang Q, Guo R, Ma Q, Sun Q, Fan Y, Xie Y, Yang Z, Jie Z, Zhao B, Xiao L, Yang L, Zhang T, Feng J, Guo L, He X, Chen Y, Chen C, Gao C, Xu X, Yang H, Wang J, Dang Y, Madsen L, Brix S, Kristiansen K, Jia H, Ma X. Zhu F, et al. Among authors: zhang t. Nat Commun. 2020 Mar 31;11(1):1612. doi: 10.1038/s41467-020-15457-9. Nat Commun. 2020. PMID: 32235826 Free PMC article.
Integrated genetic analyses revealed novel human longevity loci and reduced risks of multiple diseases in a cohort study of 15,651 Chinese individuals.
Liu X, Song Z, Li Y, Yao Y, Fang M, Bai C, An P, Chen H, Chen Z, Tang B, Shen J, Gao X, Zhang M, Chen P, Zhang T, Jia H, Liu X, Hou Y, Yang H, Wang J, Wang F, Xu X, Min J, Nie C, Zeng Y. Liu X, et al. Among authors: zhang m, zhang t. Aging Cell. 2021 Mar;20(3):e13323. doi: 10.1111/acel.13323. Epub 2021 Mar 3. Aging Cell. 2021. PMID: 33657282 Free PMC article.
Deep sequencing of 1320 genes reveals the landscape of protein-truncating variants and their contribution to psoriasis in 19,973 Chinese individuals.
Xu H, Zhen Q, Bai M, Fang L, Zhang Y, Li B, Ge H, Moon S, Chen W, Fu W, Xu Q, Zhou Y, Yu Y, Lin L, Yong L, Zhang T, Chen S, Liu S, Zhang H, Chen R, Cao L, Zhang Y, Zhang R, Yang H, Hu X, Akey JM, Jin X, Sun L. Xu H, et al. Among authors: zhang r, zhang t, zhang h, zhang y. Genome Res. 2021 Jul;31(7):1150-1158. doi: 10.1101/gr.267963.120. Epub 2021 Jun 21. Genome Res. 2021. PMID: 34155038 Free PMC article.
New genetic variants associated with major adverse cardiovascular events in patients with acute coronary syndromes and treated with clopidogrel and aspirin.
Liu X, Xu H, Xu H, Geng Q, Mak WH, Ling F, Su Z, Yang F, Zhang T, Chen J, Yang H, Wang J, Zhang X, Xu X, Jia H, Zhang Z, Liu X, Zhong S. Liu X, et al. Among authors: zhang t, zhang z, zhang x. Pharmacogenomics J. 2021 Dec;21(6):664-672. doi: 10.1038/s41397-021-00245-5. Epub 2021 Jun 22. Pharmacogenomics J. 2021. PMID: 34158603 Free PMC article.
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