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A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype.
Hýžďalová M, Procházková J, Strapáčová S, Svržková L, Vacek O, Fedr R, Andrysík Z, Hrubá E, Líbalová H, Kléma J, Topinka J, Mašek J, Souček K, Vondráček J, Machala M. Hýžďalová M, et al. Among authors: hruba e. Chemosphere. 2021 Jan;263:128126. doi: 10.1016/j.chemosphere.2020.128126. Epub 2020 Sep 10. Chemosphere. 2021. PMID: 33297115
Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands.
Procházková J, Strapáčová S, Svržková L, Andrysík Z, Hýžďalová M, Hrubá E, Pěnčíková K, Líbalová H, Topinka J, Kléma J, Espinosa JM, Vondráček J, Machala M. Procházková J, et al. Among authors: hruba e. Toxicol Lett. 2018 Aug;292:162-174. doi: 10.1016/j.toxlet.2018.04.024. Epub 2018 Apr 25. Toxicol Lett. 2018. PMID: 29704546
Genotoxic polycyclic aromatic hydrocarbons fail to induce the p53-dependent DNA damage response, apoptosis or cell-cycle arrest in human prostate carcinoma LNCaP cells.
Hrubá E, Trilecová L, Marvanová S, Krcmár P, Vykopalová L, Milcová A, Líbalová H, Topinka J, Starsíchová A, Soucek K, Vondrácek J, Machala M. Hrubá E, et al. Toxicol Lett. 2010 Sep 1;197(3):227-35. doi: 10.1016/j.toxlet.2010.06.004. Epub 2010 Jun 11. Toxicol Lett. 2010. PMID: 20542099
TGF-β1 signaling plays a dominant role in the crosstalk between TGF-β1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells.
Staršíchová A, Hrubá E, Slabáková E, Pernicová Z, Procházková J, Pěnčíková K, Seda V, Kabátková M, Vondráček J, Kozubík A, Machala M, Souček K. Staršíchová A, et al. Among authors: hruba e. Cell Signal. 2012 Aug;24(8):1665-76. doi: 10.1016/j.cellsig.2012.04.008. Epub 2012 Apr 25. Cell Signal. 2012. PMID: 22560882
In Vitro Transformation of Human Bronchial Epithelial Cells by Diesel Exhaust Particles: Gene Expression Profiling and Early Toxic Responses.
Rynning I, Neca J, Vrbova K, Libalova H, Rossner P Jr, Holme JA, Gützkow KB, Afanou AKJ, Arnoldussen YJ, Hruba E, Skare Ø, Haugen A, Topinka J, Machala M, Mollerup S. Rynning I, et al. Among authors: hruba e. Toxicol Sci. 2018 Nov 1;166(1):51-64. doi: 10.1093/toxsci/kfy183. Toxicol Sci. 2018. PMID: 30010986 Free PMC article.
AhR-mediated changes in global gene expression in rat liver progenitor cells.
Faust D, Vondráček J, Krčmář P, Smerdová L, Procházková J, Hrubá E, Hulinková P, Kaina B, Dietrich C, Machala M. Faust D, et al. Among authors: hruba e. Arch Toxicol. 2013 Apr;87(4):681-98. doi: 10.1007/s00204-012-0979-z. Epub 2012 Nov 30. Arch Toxicol. 2013. PMID: 23196670
Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro.
Pěnčíková K, Brenerová P, Svržková L, Hrubá E, Pálková L, Vondráček J, Lehmler HJ, Machala M. Pěnčíková K, et al. Among authors: hruba e. Environ Sci Pollut Res Int. 2018 Jun;25(17):16411-16419. doi: 10.1007/s11356-017-0683-x. Epub 2017 Nov 9. Environ Sci Pollut Res Int. 2018. PMID: 29124635 Free PMC article.
34 results