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How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling.
Latorraca NR, Masureel M, Hollingsworth SA, Heydenreich FM, Suomivuori CM, Brinton C, Townshend RJL, Bouvier M, Kobilka BK, Dror RO. Latorraca NR, et al. Cell. 2020 Dec 23;183(7):1813-1825.e18. doi: 10.1016/j.cell.2020.11.014. Epub 2020 Dec 8. Cell. 2020. PMID: 33296703 Free PMC article.
GPCR Dynamics: Structures in Motion.
Latorraca NR, Venkatakrishnan AJ, Dror RO. Latorraca NR, et al. Chem Rev. 2017 Jan 11;117(1):139-155. doi: 10.1021/acs.chemrev.6b00177. Epub 2016 Sep 13. Chem Rev. 2017. PMID: 27622975 Free article. Review.
Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, Stevens RC, Cherezov V, Gurevich VV, Griffin PR, Ernst OP, Melcher K, Xu HE. Zhou XE, et al. Among authors: latorraca nr. Cell. 2017 Jul 27;170(3):457-469.e13. doi: 10.1016/j.cell.2017.07.002. Cell. 2017. PMID: 28753425 Free PMC article.
Gi- and Gs-coupled GPCRs show different modes of G-protein binding.
Van Eps N, Altenbach C, Caro LN, Latorraca NR, Hollingsworth SA, Dror RO, Ernst OP, Hubbell WL. Van Eps N, et al. Among authors: latorraca nr. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2383-2388. doi: 10.1073/pnas.1721896115. Epub 2018 Feb 20. Proc Natl Acad Sci U S A. 2018. PMID: 29463720 Free PMC article.
Molecular mechanism of GPCR-mediated arrestin activation.
Latorraca NR, Wang JK, Bauer B, Townshend RJL, Hollingsworth SA, Olivieri JE, Xu HE, Sommer ME, Dror RO. Latorraca NR, et al. Nature. 2018 May;557(7705):452-456. doi: 10.1038/s41586-018-0077-3. Epub 2018 May 2. Nature. 2018. PMID: 29720655 Free PMC article.
Catalytic activation of β-arrestin by GPCRs.
Eichel K, Jullié D, Barsi-Rhyne B, Latorraca NR, Masureel M, Sibarita JB, Dror RO, von Zastrow M. Eichel K, et al. Among authors: latorraca nr. Nature. 2018 May;557(7705):381-386. doi: 10.1038/s41586-018-0079-1. Epub 2018 May 2. Nature. 2018. PMID: 29720660 Free PMC article.
Structure of the µ-opioid receptor-Gi protein complex.
Koehl A, Hu H, Maeda S, Zhang Y, Qu Q, Paggi JM, Latorraca NR, Hilger D, Dawson R, Matile H, Schertler GFX, Granier S, Weis WI, Dror RO, Manglik A, Skiniotis G, Kobilka BK. Koehl A, et al. Among authors: latorraca nr. Nature. 2018 Jun;558(7711):547-552. doi: 10.1038/s41586-018-0219-7. Epub 2018 Jun 13. Nature. 2018. PMID: 29899455 Free PMC article.
35 results