de Vera IMS - Search Results

1

Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1.

Munoz-Tello P, Lin H, Khan P, de Vera IMS, Kamenecka TM, Kojetin DJ. Munoz-Tello P, et al. Among authors: de vera ims. J Med Chem. 2020 Dec 24;63(24):15639-15654. doi: 10.1021/acs.jmedchem.0c00894. Epub 2020 Dec 8. J Med Chem. 2020. PMID: 33289551 Free PMC article.

2

An alternate binding site for PPARγ ligands.

Hughes TS, Giri PK, de Vera IM, Marciano DP, Kuruvilla DS, Shin Y, Blayo AL, Kamenecka TM, Burris TP, Griffin PR, Kojetin DJ. Hughes TS, et al. Nat Commun. 2014 Apr 7;5:3571. doi: 10.1038/ncomms4571. Nat Commun. 2014. PMID: 24705063 Free PMC article.

3

Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate.

Hudson WH, Pickard MR, de Vera IM, Kuiper EG, Mourtada-Maarabouni M, Conn GL, Kojetin DJ, Williams GT, Ortlund EA. Hudson WH, et al. Nat Commun. 2014 Nov 7;5:5395. doi: 10.1038/ncomms6395. Nat Commun. 2014. PMID: 25377354 Free PMC article.

4

Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection.

Hughes TS, Wilson HD, de Vera IM, Kojetin DJ. Hughes TS, et al. PLoS One. 2015 Aug 4;10(8):e0134474. doi: 10.1371/journal.pone.0134474. eCollection 2015. PLoS One. 2015. PMID: 26241959 Free PMC article.

5

Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.

Hudson WH, Kossmann BR, de Vera IM, Chuo SW, Weikum ER, Eick GN, Thornton JW, Ivanov IN, Kojetin DJ, Ortlund EA. Hudson WH, et al. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):326-31. doi: 10.1073/pnas.1518960113. Epub 2015 Dec 29. Proc Natl Acad Sci U S A. 2016. PMID: 26715749 Free PMC article.

6

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.

Thenin-Houssier S, de Vera IM, Pedro-Rosa L, Brady A, Richard A, Konnick B, Opp S, Buffone C, Fuhrmann J, Kota S, Billack B, Pietka-Ottlik M, Tellinghuisen T, Choe H, Spicer T, Scampavia L, Diaz-Griffero F, Kojetin DJ, Valente ST. Thenin-Houssier S, et al. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2195-208. doi: 10.1128/AAC.02574-15. Print 2016 Apr. Antimicrob Agents Chemother. 2016. PMID: 26810656 Free PMC article.

7

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1.

de Vera IM, Giri PK, Munoz-Tello P, Brust R, Fuhrmann J, Matta-Camacho E, Shang J, Campbell S, Wilson HD, Granados J, Gardner WJ Jr, Creamer TP, Solt LA, Kojetin DJ. de Vera IM, et al. ACS Chem Biol. 2016 Jul 15;11(7):1795-9. doi: 10.1021/acschembio.6b00037. Epub 2016 Apr 29. ACS Chem Biol. 2016. PMID: 27128111 Free PMC article.

8

Mechanistic insight into protein modification and sulfur mobilization activities of noncanonical E1 and associated ubiquitin-like proteins of Archaea.

Hepowit NL, de Vera IM, Cao S, Fu X, Wu Y, Uthandi S, Chavarria NE, Englert M, Su D, Sӧll D, Kojetin DJ, Maupin-Furlow JA. Hepowit NL, et al. FEBS J. 2016 Oct;283(19):3567-3586. doi: 10.1111/febs.13819. FEBS J. 2016. PMID: 27459543 Free PMC article.

9

Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy.

Hughes TS, Shang J, Brust R, de Vera IMS, Fuhrmann J, Ruiz C, Cameron MD, Kamenecka TM, Kojetin DJ. Hughes TS, et al. Among authors: de vera ims. J Med Chem. 2016 Nov 23;59(22):10335-10341. doi: 10.1021/acs.jmedchem.6b01340. Epub 2016 Nov 4. J Med Chem. 2016. PMID: 27783520 Free PMC article.

10

Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes.

Weikum ER, de Vera IMS, Nwachukwu JC, Hudson WH, Nettles KW, Kojetin DJ, Ortlund EA. Weikum ER, et al. Among authors: de vera ims. Nucleic Acids Res. 2017 Aug 21;45(14):8596-8608. doi: 10.1093/nar/gkx509. Nucleic Acids Res. 2017. PMID: 28591827 Free PMC article.

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