Design, synthesis, and structure-activity relationship of novel LSD1 inhibitors based on pyrimidine-thiourea hybrids as potent, orally active antitumor agents.
Ma LY, Zheng YC, Wang SQ, Wang B, Wang ZR, Pang LP, Zhang M, Wang JW, Ding L, Li J, Wang C, Hu B, Liu Y, Zhang XD, Wang JJ, Wang ZJ, Zhao W, Liu HM.
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J Med Chem. 2015 Feb 26;58(4):1705-16. doi: 10.1021/acs.jmedchem.5b00037. Epub 2015 Feb 6.
J Med Chem. 2015.
PMID: 25610955