Vittal R - Search Results

1

Loss of FOXF1 expression promotes human lung-resident mesenchymal stromal cell migration via ATX/LPA/LPA1 signaling axis.

Cao P, Walker NM, Braeuer RR, Mazzoni-Putman S, Aoki Y, Misumi K, Wheeler DS, Vittal R, Lama VN. Cao P, et al. Among authors: vittal r. Sci Rep. 2020 Dec 4;10(1):21231. doi: 10.1038/s41598-020-77601-1. Sci Rep. 2020. PMID: 33277571 Free PMC article.

2

c-Jun N-terminal kinase (JNK)-mediated induction of mSin1 expression and mTORC2 activation in mesenchymal cells during fibrosis.

Walker NM, Mazzoni SM, Vittal R, Fingar DC, Lama VN. Walker NM, et al. Among authors: vittal r. J Biol Chem. 2018 Nov 2;293(44):17229-17239. doi: 10.1074/jbc.RA118.003926. Epub 2018 Sep 14. J Biol Chem. 2018. PMID: 30217824 Free PMC article.

3

Interleukin 6 trans-signaling is a critical driver of lung allograft fibrosis.

Wheeler DS, Misumi K, Walker NM, Vittal R, Combs MP, Aoki Y, Braeuer RR, Lama VN. Wheeler DS, et al. Among authors: vittal r. Am J Transplant. 2021 Jul;21(7):2360-2371. doi: 10.1111/ajt.16417. Epub 2021 Jan 4. Am J Transplant. 2021. PMID: 33249747 Free PMC article.

4

Humoral immune responses mediate the development of a restrictive phenotype of chronic lung allograft dysfunction.

Misumi K, Wheeler DS, Aoki Y, Combs MP, Braeuer RR, Higashikubo R, Li W, Kreisel D, Vittal R, Myers J, Lagstein A, Walker NM, Farver CF, Lama VN. Misumi K, et al. Among authors: vittal r. JCI Insight. 2020 Dec 3;5(23):e136533. doi: 10.1172/jci.insight.136533. JCI Insight. 2020. PMID: 33268593 Free PMC article.

5

Transcription factor FOXF1 identifies compartmentally distinct mesenchymal cells with a role in lung allograft fibrogenesis.

Braeuer RR, Walker NM, Misumi K, Mazzoni-Putman S, Aoki Y, Liao R, Vittal R, Kleer GG, Wheeler DS, Sexton JZ, Farver CF, Welch JD, Lama VN. Braeuer RR, et al. Among authors: vittal r. J Clin Invest. 2021 Nov 1;131(21):e147343. doi: 10.1172/JCI147343. J Clin Invest. 2021. PMID: 34546975 Free PMC article.

6

Overexpression of Decay Accelerating Factor Mitigates Fibrotic Responses to Lung Injury.

Vittal R, Fisher AJ, Thompson EL, Cipolla EM, Gu H, Mickler EA, Varre A, Agarwal M, Kim KK, Vasko MR, Moore BB, Lama VN. Vittal R, et al. Am J Respir Cell Mol Biol. 2022 Oct;67(4):459-470. doi: 10.1165/rcmb.2021-0463OC. Am J Respir Cell Mol Biol. 2022. PMID: 35895592 Free PMC article.

7

The mitigating effect of exogenous carbon monoxide on chronic allograft rejection and fibrosis post-lung transplantation.

Aoki Y, Walker NM, Misumi K, Mimura T, Vittal R, McLinden AP, Fitzgerald L, Combs MP, Lyu D, Osterholzer JJ, Pinsky DJ, Lama VN. Aoki Y, et al. Among authors: vittal r. J Heart Lung Transplant. 2023 Mar;42(3):317-326. doi: 10.1016/j.healun.2022.11.005. Epub 2022 Nov 26. J Heart Lung Transplant. 2023. PMID: 36522238

8

Genetic deficiency of the transcription factor NFAT1 confers protection against fibrogenic responses independent of immune influx.

Vittal R, Walker NM, McLinden AP, Braeuer RR, Ke F, Fattahi F, Combs MP, Misumi K, Aoki Y, Wheeler DS, Wilke CA, Huang SK, Moore BB, Cao P, Lama VN. Vittal R, et al. Am J Physiol Lung Cell Mol Physiol. 2024 Jan 1;326(1):L39-L51. doi: 10.1152/ajplung.00045.2023. Epub 2023 Nov 7. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 37933452

9

MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunction.

Walker NM, Ibuki Y, McLinden AP, Misumi K, Mitchell DC, Kleer GG, Lock AM, Vittal R, Sonenberg N, Garner AL, Lama VN. Walker NM, et al. Among authors: vittal r. J Clin Invest. 2024 Aug 15;134(16):e168393. doi: 10.1172/JCI168393. J Clin Invest. 2024. PMID: 39145446 Free PMC article.

10

IL-17A deficiency mitigates bleomycin-induced complement activation during lung fibrosis.

Cipolla E, Fisher AJ, Gu H, Mickler EA, Agarwal M, Wilke CA, Kim KK, Moore BB, Vittal R. Cipolla E, et al. Among authors: vittal r. FASEB J. 2017 Dec;31(12):5543-5556. doi: 10.1096/fj.201700289R. Epub 2017 Aug 17. FASEB J. 2017. PMID: 28821630 Free PMC article.

A., Agarwal, M., Wilke, C. A., Kim, K. K., Moore, B. B., Vittal, R. IL-17A deficiency mitigates bleomycin-induced complement activation during lung fibrosis....

A., Agarwal, M., Wilke, C. A., Kim, K. K., Moore, B. B., Vittal, R. IL-17A deficiency mitigates bleomycin-induced complement a …

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