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Integrated transcriptomic and proteomic analysis indicated that neurotoxicity of rats with chronic fluorosis may be in mechanism involved in the changed cholinergic pathway and oxidative stress.
Ran LY, Xiang J, Zeng XX, Tang JL, Dong YT, Zhang F, Yu WF, Qi XL, Xiao Y, Zou J, Deng J, Guan ZZ. Ran LY, et al. Among authors: zeng xx. J Trace Elem Med Biol. 2021 Mar;64:126688. doi: 10.1016/j.jtemb.2020.126688. Epub 2020 Nov 21. J Trace Elem Med Biol. 2021. PMID: 33260044
Exposure to fluoride exacerbates the cognitive deficit of diabetic patients living in areas with endemic fluorosis, as well as of rats with type 2 diabetes induced by streptozotocin via a mechanism that may involve excessive activation of the poly(ADP ribose) polymerase-1/P53 pathway.
Xiang J, Qi XL, Cao K, Ran LY, Zeng XX, Xiao X, Liao W, He WW, Hong W, He Y, Guan ZZ. Xiang J, et al. Among authors: zeng xx. Sci Total Environ. 2024 Feb 20;912:169512. doi: 10.1016/j.scitotenv.2023.169512. Epub 2023 Dec 23. Sci Total Environ. 2024. PMID: 38145685
184 results