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Integrated transcriptomic and proteomic analysis indicated that neurotoxicity of rats with chronic fluorosis may be in mechanism involved in the changed cholinergic pathway and oxidative stress.
Ran LY, Xiang J, Zeng XX, Tang JL, Dong YT, Zhang F, Yu WF, Qi XL, Xiao Y, Zou J, Deng J, Guan ZZ. Ran LY, et al. Among authors: xiang j. J Trace Elem Med Biol. 2021 Mar;64:126688. doi: 10.1016/j.jtemb.2020.126688. Epub 2020 Nov 21. J Trace Elem Med Biol. 2021. PMID: 33260044
The neuroprotective effects of SIRT1 in mice carrying the APP/PS1 double-transgenic mutation and in SH-SY5Y cells over-expressing human APP670/671 may involve elevated levels of α7 nicotinic acetylcholine receptors.
Cao K, Dong YT, Xiang J, Xu Y, Li Y, Song H, Yu WF, Qi XL, Guan ZZ. Cao K, et al. Among authors: xiang j. Aging (Albany NY). 2020 Jan 30;12(2):1792-1807. doi: 10.18632/aging.102713. Epub 2020 Jan 30. Aging (Albany NY). 2020. PMID: 32003755 Free PMC article.
5,334 results