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Improving target assessment in biomedical research: the GOT-IT recommendations.
Emmerich CH, Gamboa LM, Hofmann MCJ, Bonin-Andresen M, Arbach O, Schendel P, Gerlach B, Hempel K, Bespalov A, Dirnagl U, Parnham MJ. Emmerich CH, et al. Among authors: bespalov a. Nat Rev Drug Discov. 2021 Jan;20(1):64-81. doi: 10.1038/s41573-020-0087-3. Epub 2020 Nov 16. Nat Rev Drug Discov. 2021. PMID: 33199880 Free PMC article. Review.
Introduction to the EQIPD quality system.
Bespalov A, Bernard R, Gilis A, Gerlach B, Guillén J, Castagné V, Lefevre IA, Ducrey F, Monk L, Bongiovanni S, Altevogt B, Arroyo-Araujo M, Bikovski L, de Bruin N, Castaños-Vélez E, Dityatev A, Emmerich CH, Fares R, Ferland-Beckham C, Froger-Colléaux C, Gailus-Durner V, Hölter SM, Hofmann MC, Kabitzke P, Kas MJ, Kurreck C, Moser P, Pietraszek M, Popik P, Potschka H, Prado Montes de Oca E, Restivo L, Riedel G, Ritskes-Hoitinga M, Samardzic J, Schunn M, Stöger C, Voikar V, Vollert J, Wever KE, Wuyts K, MacLeod MR, Dirnagl U, Steckler T. Bespalov A, et al. Elife. 2021 May 24;10:e63294. doi: 10.7554/eLife.63294. Elife. 2021. PMID: 34028353 Free PMC article.
PEERS - An Open Science "Platform for the Exchange of Experimental Research Standards" in Biomedicine.
Sil A, Bespalov A, Dalla C, Ferland-Beckham C, Herremans A, Karantzalos K, Kas MJ, Kokras N, Parnham MJ, Pavlidi P, Pristouris K, Steckler T, Riedel G, Emmerich CH. Sil A, et al. Among authors: bespalov a. Front Behav Neurosci. 2021 Oct 21;15:755812. doi: 10.3389/fnbeh.2021.755812. eCollection 2021. Front Behav Neurosci. 2021. PMID: 34744655 Free PMC article.
Towards best practices in research: Role of academic core facilities.
Restivo L, Gerlach B, Tsoory M, Bikovski L, Badurek S, Pitzer C, Kos-Braun IC, Mausset-Bonnefont AM, Ward J, Schunn M, Noldus LP, Bespalov A, Voikar V. Restivo L, et al. Among authors: bespalov a. EMBO Rep. 2021 Dec 6;22(12):e53824. doi: 10.15252/embr.202153824. Epub 2021 Nov 4. EMBO Rep. 2021. PMID: 34734666 Free PMC article.
Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals.
Vollert J, Schenker E, Macleod M, Bespalov A, Wuerbel H, Michel M, Dirnagl U, Potschka H, Waldron AM, Wever K, Steckler T, van de Casteele T, Altevogt B, Sil A, Rice ASC; EQIPD WP3 study group members. Vollert J, et al. Among authors: bespalov a. BMJ Open Sci. 2020 Apr 15;4(1):e100046. doi: 10.1136/bmjos-2019-100046. eCollection 2020. BMJ Open Sci. 2020. PMID: 35047688 Free PMC article.
Failed trials for central nervous system disorders do not necessarily invalidate preclinical models and drug targets.
Bespalov A, Steckler T, Altevogt B, Koustova E, Skolnick P, Deaver D, Millan MJ, Bastlund JF, Doller D, Witkin J, Moser P, O'Donnell P, Ebert U, Geyer MA, Prinssen E, Ballard T, Macleod M. Bespalov A, et al. Nat Rev Drug Discov. 2016 Jul;15(7):516. doi: 10.1038/nrd.2016.88. Epub 2016 Jun 17. Nat Rev Drug Discov. 2016. PMID: 27312728 No abstract available.
167 results