Ruf S - Search Results

1

Using Graph Databases to Investigate Trends in Structure-Activity Relationship Networks.

Matter H, Buning C, Stefanescu DD, Ruf S, Hessler G. Matter H, et al. Among authors: ruf s. J Chem Inf Model. 2020 Dec 28;60(12):6120-6134. doi: 10.1021/acs.jcim.0c00947. Epub 2020 Nov 27. J Chem Inf Model. 2020. PMID: 33245234

2

Novel β-amino acid derivatives as inhibitors of cathepsin A.

Ruf S, Buning C, Schreuder H, Horstick G, Linz W, Olpp T, Pernerstorfer J, Hiss K, Kroll K, Kannt A, Kohlmann M, Linz D, Hübschle T, Rütten H, Wirth K, Schmidt T, Sadowski T. Ruf S, et al. J Med Chem. 2012 Sep 13;55(17):7636-49. doi: 10.1021/jm300663n. Epub 2012 Aug 16. J Med Chem. 2012. PMID: 22861813

3

Identification of high-affinity P2Y₁₂ antagonists based on a phenylpyrazole glutamic acid piperazine backbone.

Zech G, Hessler G, Evers A, Weiss T, Florian P, Just M, Czech J, Czechtizky W, Görlitzer J, Ruf S, Kohlmann M, Nazaré M. Zech G, et al. Among authors: ruf s. J Med Chem. 2012 Oct 25;55(20):8615-29. doi: 10.1021/jm300771j. Epub 2012 Oct 4. J Med Chem. 2012. PMID: 22984835

4

Inhibition of CatA: an emerging strategy for the treatment of heart failure.

Ruf S, Buning C, Schreuder H, Linz W, Hübschle T, Linz D, Ruetten H, Wirth K, Sadowski T. Ruf S, et al. Future Med Chem. 2013 Mar;5(4):399-409. doi: 10.4155/fmc.13.24. Future Med Chem. 2013. PMID: 23495688

5

Crystal structure of cathepsin A, a novel target for the treatment of cardiovascular diseases.

Schreuder HA, Liesum A, Kroll K, Böhnisch B, Buning C, Ruf S, Sadowski T. Schreuder HA, et al. Among authors: ruf s. Biochem Biophys Res Commun. 2014 Mar 7;445(2):451-6. doi: 10.1016/j.bbrc.2014.02.014. Epub 2014 Feb 12. Biochem Biophys Res Commun. 2014. PMID: 24530914

6

A Solid Supported Membrane-Based Technology for Electrophysical Screening of B⁰AT1-Modulating Compounds.

Gerbeth-Kreul C, Pommereau A, Ruf S, Kane JL Jr, Kuntzweiler T, Hessler G, Engel CK, Shum P, Wei L, Czech J, Licher T. Gerbeth-Kreul C, et al. Among authors: ruf s. SLAS Discov. 2021 Jul;26(6):783-797. doi: 10.1177/24725552211011180. Epub 2021 May 6. SLAS Discov. 2021. PMID: 33955247 Free article.

7

The PROTACtable genome.

Schneider M, Radoux CJ, Hercules A, Ochoa D, Dunham I, Zalmas LP, Hessler G, Ruf S, Shanmugasundaram V, Hann MM, Thomas PJ, Queisser MA, Benowitz AB, Brown K, Leach AR. Schneider M, et al. Among authors: ruf s. Nat Rev Drug Discov. 2021 Oct;20(10):789-797. doi: 10.1038/s41573-021-00245-x. Epub 2021 Jul 20. Nat Rev Drug Discov. 2021. PMID: 34285415 Review.

8

Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase.

Ruf S, Hallur MS, Anchan NK, Swamy IN, Murugesan KR, Sarkar S, Narasimhulu LK, Putta VPRK, Shaik S, Chandrasekar DV, Mane VS, Kadnur SV, Suresh J, Bhamidipati RK, Singh M, Burri RR, Kristam R, Schreuder H, Czech J, Rudolph C, Marker A, Langer T, Mullangi R, Yura T, Gosu R, Kannt A, Dhakshinamoorthy S, Rajagopal S. Ruf S, et al. Bioorg Med Chem Lett. 2018 Mar 1;28(5):922-925. doi: 10.1016/j.bmcl.2018.01.058. Epub 2018 Jan 31. Bioorg Med Chem Lett. 2018. PMID: 29433927

9

Identification and synthesis of novel inhibitors of acetyl-CoA carboxylase with in vitro and in vivo efficacy on fat oxidation.

Keil S, Müller M, Zoller G, Haschke G, Schroeter K, Glien M, Ruf S, Focken I, Herling AW, Schmoll D. Keil S, et al. Among authors: ruf s. J Med Chem. 2010 Dec 23;53(24):8679-87. doi: 10.1021/jm101179e. Epub 2010 Nov 17. J Med Chem. 2010. PMID: 21082864

10

Metal-free electrochemical fluorodecarboxylation of aryloxyacetic acids to fluoromethyl aryl ethers.

Berger M, Herszman JD, Kurimoto Y, de Kruijff GHM, Schüll A, Ruf S, Waldvogel SR. Berger M, et al. Among authors: ruf s. Chem Sci. 2020 Jun 1;11(23):6053-6057. doi: 10.1039/d0sc02417a. Chem Sci. 2020. PMID: 34094098 Free PMC article.

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