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Page 1
Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability.
Brouwer PJM, Caniels TG, van der Straten K, Snitselaar JL, Aldon Y, Bangaru S, Torres JL, Okba NMA, Claireaux M, Kerster G, Bentlage AEH, van Haaren MM, Guerra D, Burger JA, Schermer EE, Verheul KD, van der Velde N, van der Kooi A, van Schooten J, van Breemen MJ, Bijl TPL, Sliepen K, Aartse A, Derking R, Bontjer I, Kootstra NA, Wiersinga WJ, Vidarsson G, Haagmans BL, Ward AB, de Bree GJ, Sanders RW, van Gils MJ. Brouwer PJM, et al. Among authors: van der kooi a, van breemen mj, van der velde n, van schooten j, van gils mj, van der straten k, van haaren mm. Science. 2020 Aug 7;369(6504):643-650. doi: 10.1126/science.abc5902. Epub 2020 Jun 15. Science. 2020. PMID: 32540902 Free PMC article.
Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity.
Liu H, Wu NC, Yuan M, Bangaru S, Torres JL, Caniels TG, van Schooten J, Zhu X, Lee CD, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. Liu H, et al. Among authors: van schooten j, van gils mj. bioRxiv [Preprint]. 2020 Aug 3:2020.08.02.233536. doi: 10.1101/2020.08.02.233536. bioRxiv. 2020. Update in: Immunity. 2020 Dec 15;53(6):1272-1280.e5. doi: 10.1016/j.immuni.2020.10.023 PMID: 32793906 Free PMC article. Updated. Preprint.
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, Nogal B, Sok D, Rakasz EG, Labranche C, Vigdorovich V, Christley S, Carnathan DG, Sather DN, Montefiori D, Silvestri G, Burton DR, Moore JP, Wilson IA, Sanders RW, Ward AB, van Gils MJ. Cottrell CA, et al. Among authors: van schooten j, van gils mj, van breemen m, van der woude p. PLoS Pathog. 2020 Aug 31;16(8):e1008753. doi: 10.1371/journal.ppat.1008753. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32866207 Free PMC article.
Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection.
Brouwer PJM, Brinkkemper M, Maisonnasse P, Dereuddre-Bosquet N, Grobben M, Claireaux M, de Gast M, Marlin R, Chesnais V, Diry S, Allen JD, Watanabe Y, Giezen JM, Kerster G, Turner HL, van der Straten K, van der Linden CA, Aldon Y, Naninck T, Bontjer I, Burger JA, Poniman M, Mykytyn AZ, Okba NMA, Schermer EE, van Breemen MJ, Ravichandran R, Caniels TG, van Schooten J, Kahlaoui N, Contreras V, Lemaître J, Chapon C, Fang RHT, Villaudy J, Sliepen K, van der Velden YU, Haagmans BL, de Bree GJ, Ginoux E, Ward AB, Crispin M, King NP, van der Werf S, van Gils MJ, Le Grand R, Sanders RW. Brouwer PJM, et al. Among authors: van breemen mj, van schooten j, van der velden yu, van gils mj, van der linden ca, van der straten k, van der werf s. Cell. 2021 Mar 4;184(5):1188-1200.e19. doi: 10.1016/j.cell.2021.01.035. Epub 2021 Jan 26. Cell. 2021. PMID: 33577765 Free PMC article.
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models.
Maisonnasse P, Aldon Y, Marc A, Marlin R, Dereuddre-Bosquet N, Kuzmina NA, Freyn AW, Snitselaar JL, Gonçalves A, Caniels TG, Burger JA, Poniman M, Chesnais V, Diry S, Iershov A, Ronk AJ, Jangra S, Rathnasinghe R, Brouwer P, Bijl T, van Schooten J, Brinkkemper M, Liu H, Yuan M, Mire CE, van Breemen MJ, Contreras V, Naninck T, Lemaître J, Kahlaoui N, Relouzat F, Chapon C, Ho Tsong Fang R, McDanal C, Osei-Twum M, St-Amant N, Gagnon L, Montefiori DC, Wilson IA, Ginoux E, de Bree GJ, García-Sastre A, Schotsaert M, Coughlan L, Bukreyev A, van der Werf S, Guedj J, Sanders RW, van Gils MJ, Le Grand R. Maisonnasse P, et al. Among authors: van breemen mj, van schooten j, van gils mj, van der werf s. Res Sq [Preprint]. 2021 Feb 15:rs.3.rs-235272. doi: 10.21203/rs.3.rs-235272/v1. Res Sq. 2021. Update in: Nat Commun. 2021 Oct 20;12(1):6097. doi: 10.1038/s41467-021-26354-0 PMID: 33619476 Free PMC article. Updated. Preprint.
Fusion peptide priming reduces immune responses to HIV-1 envelope trimer base.
Corrigan AR, Duan H, Cheng C, Gonelli CA, Ou L, Xu K, DeMouth ME, Geng H, Narpala S, O'Connell S, Zhang B, Zhou T, Basappa M, Boyington JC, Chen SJ, O'Dell S, Pegu A, Stephens T, Tsybovsky Y, van Schooten J, Todd JP, Wang S; VRC Production Program; Doria-Rose NA, Foulds KE, Koup RA, McDermott AB, van Gils MJ, Kwong PD, Mascola JR. Corrigan AR, et al. Among authors: van schooten j, van gils mj. Cell Rep. 2021 Apr 6;35(1):108937. doi: 10.1016/j.celrep.2021.108937. Cell Rep. 2021. PMID: 33826898 Free PMC article.
Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates.
van Schooten J, van Haaren MM, Li H, McCoy LE, Havenar-Daughton C, Cottrell CA, Burger JA, van der Woude P, Helgers LC, Tomris I, Labranche CC, Montefiori DC, Ward AB, Burton DR, Moore JP, Sanders RW, Crotty S, Shaw GM, van Gils MJ. van Schooten J, et al. Among authors: van gils mj, van der woude p, van haaren mm. PLoS Pathog. 2021 Aug 25;17(8):e1009736. doi: 10.1371/journal.ppat.1009736. eCollection 2021 Aug. PLoS Pathog. 2021. PMID: 34432859 Free PMC article.
The Glycan Hole Area of HIV-1 Envelope Trimers Contributes Prominently to the Induction of Autologous Neutralization.
Schorcht A, Cottrell CA, Pugach P, Ringe RP, Han AX, Allen JD, van den Kerkhof TLGM, Seabright GE, Schermer EE, Ketas TJ, Burger JA, van Schooten J, LaBranche CC, Ozorowski G, de Val N, Bader DLV, Schuitemaker H, Russell CA, Montefiori DC, van Gils MJ, Crispin M, Klasse PJ, Ward AB, Moore JP, Sanders RW. Schorcht A, et al. Among authors: van schooten j, van gils mj, van den kerkhof tlgm. J Virol. 2022 Jan 12;96(1):e0155221. doi: 10.1128/JVI.01552-21. Epub 2021 Oct 20. J Virol. 2022. PMID: 34669426 Free PMC article.
22 results