Löffler H - Search Results

1

Adding cetuximab to paclitaxel and carboplatin for first-line treatment of carcinoma of unknown primary (CUP): results of the Phase 2 AIO trial PACET-CUP.

Folprecht G, Trautmann K, Stein A, Huebner G, Stahl M, Kasper S, Kretzschmar A, Köhne CH, Grünwald V, Hofheinz RD, Schütte K, Löffler H, Bokemeyer C, Krämer A; Arbeitsgemeinschaft Internistische Onkologie (AIO) - CUP Group. Folprecht G, et al. Among authors: loffler h. Br J Cancer. 2021 Feb;124(4):721-727. doi: 10.1038/s41416-020-01141-8. Epub 2020 Nov 25. Br J Cancer. 2021. PMID: 33235314 Free PMC article. Clinical Trial.

2

Structure meets function--centrosomes, genome maintenance and the DNA damage response.

Löffler H, Lukas J, Bartek J, Krämer A. Löffler H, et al. Exp Cell Res. 2006 Aug 15;312(14):2633-40. doi: 10.1016/j.yexcr.2006.06.008. Epub 2006 Jun 20. Exp Cell Res. 2006. PMID: 16854412 Review.

3

Chk1-dependent regulation of Cdc25B functions to coordinate mitotic events.

Löffler H, Rebacz B, Ho AD, Lukas J, Bartek J, Krämer A. Löffler H, et al. Cell Cycle. 2006 Nov 1;5(21):2543-7. doi: 10.4161/cc.5.21.3435. Epub 2006 Sep 25. Cell Cycle. 2006. PMID: 17106257

4

Identification of griseofulvin as an inhibitor of centrosomal clustering in a phenotype-based screen.

Rebacz B, Larsen TO, Clausen MH, Rønnest MH, Löffler H, Ho AD, Krämer A. Rebacz B, et al. Among authors: loffler h. Cancer Res. 2007 Jul 1;67(13):6342-50. doi: 10.1158/0008-5472.CAN-07-0663. Cancer Res. 2007. PMID: 17616693

5

DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function.

Löffler H, Bochtler T, Fritz B, Tews B, Ho AD, Lukas J, Bartek J, Krämer A. Löffler H, et al. Cell Cycle. 2007 Oct 15;6(20):2541-8. doi: 10.4161/cc.6.20.4810. Epub 2007 Jul 30. Cell Cycle. 2007. PMID: 17726372

6

Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group.

Heilig CE, Löffler H, Mahlknecht U, Janssen JW, Ho AD, Jauch A, Krämer A. Heilig CE, et al. Among authors: loffler h. J Cell Mol Med. 2010 Apr;14(4):895-902. doi: 10.1111/j.1582-4934.2009.00905.x. Epub 2009 Sep 14. J Cell Mol Med. 2010. PMID: 19754665 Free PMC article.

7

Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance.

Löffler H, Fechter A, Matuszewska M, Saffrich R, Mistrik M, Marhold J, Hornung C, Westermann F, Bartek J, Krämer A. Löffler H, et al. Cancer Res. 2011 Mar 15;71(6):2129-39. doi: 10.1158/0008-5472.CAN-10-2684. Cancer Res. 2011. PMID: 21406398

8

Overexpression of EVI1 interferes with cytokinesis and leads to accumulation of cells with supernumerary centrosomes in G0/1 phase.

Karakaya K, Herbst F, Ball C, Glimm H, Krämer A, Löffler H. Karakaya K, et al. Among authors: loffler h. Cell Cycle. 2012 Sep 15;11(18):3492-503. doi: 10.4161/cc.21801. Epub 2012 Aug 16. Cell Cycle. 2012. PMID: 22894935 Free PMC article.

9

Patients with cancer of unknown primary: a retrospective analysis of 223 patients with adenocarcinoma or undifferentiated carcinoma.

Löffler H, Puthenparambil J, Hielscher T, Neben K, Krämer A. Löffler H, et al. Dtsch Arztebl Int. 2014 Jul 7;111(27-28):481-7. doi: 10.3238/arztebl.2014.0481. Dtsch Arztebl Int. 2014. PMID: 25138727 Free PMC article.

10

Cep63 recruits cdk1 to the centrosome-letter.

Alsara M, Löffler H, Fechter A, Bartek J, Krämer A. Alsara M, et al. Among authors: loffler h. Cancer Res. 2015 Feb 15;75(4):777-8. doi: 10.1158/0008-5472.CAN-14-3431. Epub 2015 Feb 2. Cancer Res. 2015. PMID: 25643699 No abstract available.

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