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Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells.
Eisinger S, Sarhan D, Boura VF, Ibarlucea-Benitez I, Tyystjärvi S, Oliynyk G, Arsenian-Henriksson M, Lane D, Wikström SL, Kiessling R, Virgilio T, Gonzalez SF, Kaczynska D, Kanatani S, Daskalaki E, Wheelock CE, Sedimbi S, Chambers BJ, Ravetch JV, Karlsson MCI. Eisinger S, et al. Among authors: kanatani s. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):32005-32016. doi: 10.1073/pnas.2015343117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229588 Free PMC article.
Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies.
Tanaka N, Kanatani S, Kaczynska D, Fukumoto K, Louhivuori L, Mizutani T, Kopper O, Kronqvist P, Robertson S, Lindh C, Kis L, Pronk R, Niwa N, Matsumoto K, Oya M, Miyakawa A, Falk A, Hartman J, Sahlgren C, Clevers H, Uhlén P. Tanaka N, et al. Among authors: kanatani s. Nat Biomed Eng. 2020 Sep;4(9):875-888. doi: 10.1038/s41551-020-0576-z. Epub 2020 Jun 29. Nat Biomed Eng. 2020. PMID: 32601394
Disrupted Cacna1c gene expression perturbs spontaneous Ca2+ activity causing abnormal brain development and increased anxiety.
Smedler E, Louhivuori L, Romanov RA, Masini D, Dehnisch Ellström I, Wang C, Caramia M, West Z, Zhang S, Rebellato P, Malmersjö S, Brusini I, Kanatani S, Fisone G, Harkany T, Uhlén P. Smedler E, et al. Among authors: kanatani s. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2108768119. doi: 10.1073/pnas.2108768119. Proc Natl Acad Sci U S A. 2022. PMID: 35135875 Free PMC article.
Neural progenitors organize in small-world networks to promote cell proliferation.
Malmersjö S, Rebellato P, Smedler E, Planert H, Kanatani S, Liste I, Nanou E, Sunner H, Abdelhady S, Zhang S, Andäng M, El Manira A, Silberberg G, Arenas E, Uhlén P. Malmersjö S, et al. Among authors: kanatani s. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):E1524-32. doi: 10.1073/pnas.1220179110. Epub 2013 Apr 1. Proc Natl Acad Sci U S A. 2013. PMID: 23576737 Free PMC article.
The COUP-TFII/Neuropilin-2 is a molecular switch steering diencephalon-derived GABAergic neurons in the developing mouse brain.
Kanatani S, Honda T, Aramaki M, Hayashi K, Kubo K, Ishida M, Tanaka DH, Kawauchi T, Sekine K, Kusuzawa S, Kawasaki T, Hirata T, Tabata H, Uhlén P, Nakajima K. Kanatani S, et al. Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):E4985-94. doi: 10.1073/pnas.1420701112. Epub 2015 Aug 24. Proc Natl Acad Sci U S A. 2015. PMID: 26305926 Free PMC article.
Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity.
Tanaka N, Kanatani S, Tomer R, Sahlgren C, Kronqvist P, Kaczynska D, Louhivuori L, Kis L, Lindh C, Mitura P, Stepulak A, Corvigno S, Hartman J, Micke P, Mezheyeuski A, Strell C, Carlson JW, Fernández Moro C, Dahlstrand H, Östman A, Matsumoto K, Wiklund P, Oya M, Miyakawa A, Deisseroth K, Uhlén P. Tanaka N, et al. Among authors: kanatani s. Nat Biomed Eng. 2017 Oct;1(10):796-806. doi: 10.1038/s41551-017-0139-0. Epub 2017 Oct 2. Nat Biomed Eng. 2017. PMID: 31015588
Publisher Correction: Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity.
Tanaka N, Kanatani S, Tomer R, Sahlgren C, Kronqvist P, Kaczynska D, Louhivuori L, Kis L, Lindh C, Mitura P, Stepulak A, Corvigno S, Hartman J, Micke P, Mezheyeuski A, Strell C, Carlson JW, Fernández Moro C, Dahlstrand H, Östman A, Matsumoto K, Wiklund P, Oya M, Miyakawa A, Deisseroth K, Uhlén P. Tanaka N, et al. Among authors: kanatani s. Nat Biomed Eng. 2018 Jan;2(1):48. doi: 10.1038/s41551-017-0162-1. Nat Biomed Eng. 2018. PMID: 31015657
GIT1 protects against breast cancer growth through negative regulation of Notch.
Zhang S, Miyakawa A, Wickström M, Dyberg C, Louhivuori L, Varas-Godoy M, Kemppainen K, Kanatani S, Kaczynska D, Ellström ID, Elfman L, Kronqvist P, Repo H, Mikoshiba K, Sahlgren C, Johnsen JI, Uhlén P. Zhang S, et al. Among authors: kanatani s. Nat Commun. 2022 Mar 22;13(1):1537. doi: 10.1038/s41467-022-28631-y. Nat Commun. 2022. PMID: 35318302 Free PMC article.
52 results