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Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.
Mayrhofer JE, Enzler F, Feichtner A, Röck R, Fleischmann J, Raffeiner A, Tschaikner P, Ogris E, Huber RG, Hartl M, Schneider R, Troppmair J, Torres-Quesada O, Stefan E. Mayrhofer JE, et al. Among authors: schneider r. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31105-31113. doi: 10.1073/pnas.2012150117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229534 Free PMC article.
Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling.
Kickstein E, Krauss S, Thornhill P, Rutschow D, Zeller R, Sharkey J, Williamson R, Fuchs M, Köhler A, Glossmann H, Schneider R, Sutherland C, Schweiger S. Kickstein E, et al. Among authors: schneider r. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21830-5. doi: 10.1073/pnas.0912793107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098287 Free PMC article.
A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling.
Köhler A, Demir U, Kickstein E, Krauss S, Aigner J, Aranda-Orgillés B, Karagiannidis AI, Achmüller C, Bu H, Wunderlich A, Schweiger MR, Schaefer G, Schweiger S, Klocker H, Schneider R. Köhler A, et al. Among authors: schneider r. Mol Cancer. 2014 Jun 9;13:146. doi: 10.1186/1476-4598-13-146. Mol Cancer. 2014. PMID: 24913494 Free PMC article.
A-overhang-dependent repeat expansion determination (ADRED).
Achmüller C, Köhler A, Bösch S, Schneider R. Achmüller C, et al. Among authors: schneider r. Biotechniques. 2008 Nov;45(5):577-80. doi: 10.2144/000112948. Biotechniques. 2008. PMID: 19007342 Free article.
The E3 ubiquitin ligase MID1 catalyzes ubiquitination and cleavage of Fu.
Schweiger S, Dorn S, Fuchs M, Köhler A, Matthes F, Müller EC, Wanker E, Schneider R, Krauß S. Schweiger S, et al. Among authors: schneider r. J Biol Chem. 2014 Nov 14;289(46):31805-31817. doi: 10.1074/jbc.M113.541219. Epub 2014 Oct 2. J Biol Chem. 2014. PMID: 25278022 Free PMC article.
3,973 results