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Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.
Mayrhofer JE, Enzler F, Feichtner A, Röck R, Fleischmann J, Raffeiner A, Tschaikner P, Ogris E, Huber RG, Hartl M, Schneider R, Troppmair J, Torres-Quesada O, Stefan E. Mayrhofer JE, et al. Among authors: hartl m. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31105-31113. doi: 10.1073/pnas.2012150117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229534 Free PMC article.
Inhibitor of MYC identified in a Kröhnke pyridine library.
Hart JR, Garner AL, Yu J, Ito Y, Sun M, Ueno L, Rhee JK, Baksh MM, Stefan E, Hartl M, Bister K, Vogt PK, Janda KD. Hart JR, et al. Among authors: hartl m. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12556-61. doi: 10.1073/pnas.1319488111. Epub 2014 Aug 11. Proc Natl Acad Sci U S A. 2014. PMID: 25114221 Free PMC article.
Calcium-dependent binding of Myc to calmodulin.
Raffeiner P, Schraffl A, Schwarz T, Röck R, Ledolter K, Hartl M, Konrat R, Stefan E, Bister K. Raffeiner P, et al. Among authors: hartl m. Oncotarget. 2017 Jan 10;8(2):3327-3343. doi: 10.18632/oncotarget.13759. Oncotarget. 2017. PMID: 27926480 Free PMC article.
245 results