Kirik D - Search Results

1

Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease.

Marmion DJ, Rutkowski AA, Chatterjee D, Hiller BM, Werner MH, Bezard E, Kirik D, McCown T, Gray SJ, Kordower JH. Marmion DJ, et al. Among authors: kirik d. Neurobiol Dis. 2021 Jan;148:105184. doi: 10.1016/j.nbd.2020.105184. Epub 2020 Nov 19. Neurobiol Dis. 2021. PMID: 33221532 Free article.

2

Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates.

Mandel RJ, Marmion DJ, Kirik D, Chu Y, Heindel C, McCown T, Gray SJ, Kordower JH. Mandel RJ, et al. Among authors: kirik d. Acta Neuropathol Commun. 2017 Jun 16;5(1):47. doi: 10.1186/s40478-017-0451-7. Acta Neuropathol Commun. 2017. PMID: 28619074 Free PMC article.

3

Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates.

Dodiya HB, Bjorklund T, Stansell J 3rd, Mandel RJ, Kirik D, Kordower JH. Dodiya HB, et al. Among authors: kirik d. Mol Ther. 2010 Mar;18(3):579-87. doi: 10.1038/mt.2009.216. Epub 2009 Sep 22. Mol Ther. 2010. PMID: 19773746 Free PMC article.

4

Introduction: gene therapy has gone from a pipe dream to clinical reality.

Kordower JH, Kirik D. Kordower JH, et al. Among authors: kirik d. Neurobiol Dis. 2012 Nov;48(2):151-2. doi: 10.1016/j.nbd.2012.07.014. Epub 2012 Jul 20. Neurobiol Dis. 2012. PMID: 22841531 No abstract available.

5

Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease.

Cederfjäll E, Nilsson N, Sahin G, Chu Y, Nikitidou E, Björklund T, Kordower JH, Kirik D. Cederfjäll E, et al. Among authors: kirik d. Sci Rep. 2013;3:2157. doi: 10.1038/srep02157. Sci Rep. 2013. PMID: 23831692 Free PMC article.

6

Animal models of Parkinson's disease: limits and relevance to neuroprotection studies.

Bezard E, Yue Z, Kirik D, Spillantini MG. Bezard E, et al. Among authors: kirik d. Mov Disord. 2013 Jan;28(1):61-70. doi: 10.1002/mds.25108. Epub 2012 Jul 2. Mov Disord. 2013. PMID: 22753348 Free PMC article. Review.

7

Ser129 phosphorylation of endogenous α-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function.

Buck K, Landeck N, Ulusoy A, Majbour NK, El-Agnaf OM, Kirik D. Buck K, et al. Among authors: kirik d. Neurobiol Dis. 2015 Jun;78:100-14. doi: 10.1016/j.nbd.2015.03.008. Epub 2015 Mar 25. Neurobiol Dis. 2015. PMID: 25818009

8

DNAJB6 suppresses alpha-synuclein induced pathology in an animal model of Parkinson's disease.

Arkan S, Ljungberg M, Kirik D, Hansen C. Arkan S, et al. Among authors: kirik d. Neurobiol Dis. 2021 Oct;158:105477. doi: 10.1016/j.nbd.2021.105477. Epub 2021 Aug 11. Neurobiol Dis. 2021. PMID: 34390836 Free article.

9

Ventral tegmental area dopamine neurons are resistant to human mutant alpha-synuclein overexpression.

Maingay M, Romero-Ramos M, Carta M, Kirik D. Maingay M, et al. Among authors: kirik d. Neurobiol Dis. 2006 Sep;23(3):522-32. doi: 10.1016/j.nbd.2006.04.007. Epub 2006 Jun 30. Neurobiol Dis. 2006. PMID: 16806952

10

Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons.

Ulusoy A, Björklund T, Buck K, Kirik D. Ulusoy A, et al. Among authors: kirik d. Neurobiol Dis. 2012 Sep;47(3):367-77. doi: 10.1016/j.nbd.2012.05.012. Epub 2012 May 31. Neurobiol Dis. 2012. PMID: 22659302

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