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Page 1
Crystal Structure of a Bivalent Antibody Fab Fragment.
Shahid S, Gao M, Travis Gallagher D, Pozharski E, Brinson RG, Keck ZY, Foung SKH, Fuerst TR, Mariuzza RA. Shahid S, et al. Among authors: fuerst tr. J Mol Biol. 2021 Jan 22;433(2):166714. doi: 10.1016/j.jmb.2020.11.013. Epub 2020 Nov 19. J Mol Biol. 2021. PMID: 33220264
Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice.
Keck ZY, Wang Y, Lau P, Lund G, Rangarajan S, Fauvelle C, Liao GC, Holtsberg FW, Warfield KL, Aman MJ, Pierce BG, Fuerst TR, Bailey JR, Baumert TF, Mariuzza RA, Kneteman NM, Foung SK. Keck ZY, et al. Among authors: fuerst tr. Hepatology. 2016 Dec;64(6):1922-1933. doi: 10.1002/hep.28850. Epub 2016 Oct 28. Hepatology. 2016. PMID: 27641232 Free PMC article.
In vivo combination of human anti-envelope glycoprotein E2 and -Claudin-1 monoclonal antibodies for prevention of hepatitis C virus infection.
Mailly L, Wrensch F, Heydmann L, Fauvelle C, Brignon N, Zeisel MB, Pessaux P, Keck ZY, Schuster C, Fuerst TR, Foung SKH, Baumert TF. Mailly L, et al. Among authors: fuerst tr. Antiviral Res. 2019 Feb;162:136-141. doi: 10.1016/j.antiviral.2018.12.018. Epub 2018 Dec 30. Antiviral Res. 2019. PMID: 30599173 Free PMC article.
Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells.
Urbanowicz RA, Wang R, Schiel JE, Keck ZY, Kerzic MC, Lau P, Rangarajan S, Garagusi KJ, Tan L, Guest JD, Ball JK, Pierce BG, Mariuzza RA, Foung SKH, Fuerst TR. Urbanowicz RA, et al. Among authors: fuerst tr. J Virol. 2019 Mar 21;93(7):e01403-18. doi: 10.1128/JVI.01403-18. Print 2019 Apr 1. J Virol. 2019. PMID: 30651366 Free PMC article.
Structure-Based Design of Hepatitis C Virus E2 Glycoprotein Improves Serum Binding and Cross-Neutralization.
Pierce BG, Keck ZY, Wang R, Lau P, Garagusi K, Elkholy K, Toth EA, Urbanowicz RA, Guest JD, Agnihotri P, Kerzic MC, Marin A, Andrianov AK, Ball JK, Mariuzza RA, Fuerst TR, Foung SKH. Pierce BG, et al. Among authors: fuerst tr. J Virol. 2020 Oct 27;94(22):e00704-20. doi: 10.1128/JVI.00704-20. Print 2020 Oct 27. J Virol. 2020. PMID: 32878891 Free PMC article.
Design of a native-like secreted form of the hepatitis C virus E1E2 heterodimer.
Guest JD, Wang R, Elkholy KH, Chagas A, Chao KL, Cleveland TE 4th, Kim YC, Keck ZY, Marin A, Yunus AS, Mariuzza RA, Andrianov AK, Toth EA, Foung SKH, Pierce BG, Fuerst TR. Guest JD, et al. Among authors: fuerst tr. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2015149118. doi: 10.1073/pnas.2015149118. Proc Natl Acad Sci U S A. 2021. PMID: 33431677 Free PMC article.
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