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Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood.
Quancard J, Simic O, Pissot Soldermann C, Aichholz R, Blatter M, Renatus M, Erbel P, Melkko S, Endres R, Sorge M, Kieffer L, Wagner T, Beltz K, Mcsheehy P, Wartmann M, Régnier CH, Calzascia T, Radimerski T, Bigaud M, Weiss A, Bornancin F, Schlapbach A. Quancard J, et al. Among authors: endres r. J Med Chem. 2020 Dec 10;63(23):14594-14608. doi: 10.1021/acs.jmedchem.0c01246. Epub 2020 Nov 20. J Med Chem. 2020. PMID: 33216547
N-aryl-piperidine-4-carboxamides as a novel class of potent inhibitors of MALT1 proteolytic activity.
Schlapbach A, Revesz L, Pissot Soldermann C, Zoller T, Régnier CH, Bornancin F, Radimerski T, Blank J, Schuffenhauer A, Renatus M, Erbel P, Melkko S, Heng R, Simic O, Endres R, Wartmann M, Quancard J. Schlapbach A, et al. Among authors: endres r. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2153-2158. doi: 10.1016/j.bmcl.2018.05.017. Epub 2018 May 9. Bioorg Med Chem Lett. 2018. PMID: 29759726
Discovery of Potent, Highly Selective, and In Vivo Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing.
Pissot Soldermann C, Simic O, Renatus M, Erbel P, Melkko S, Wartmann M, Bigaud M, Weiss A, McSheehy P, Endres R, Santos P, Blank J, Schuffenhauer A, Bold G, Buschmann N, Zoller T, Altmann E, Manley PW, Dix I, Buchdunger E, Scesa J, Quancard J, Schlapbach A, Bornancin F, Radimerski T, Régnier CH. Pissot Soldermann C, et al. Among authors: endres r. J Med Chem. 2020 Dec 10;63(23):14576-14593. doi: 10.1021/acs.jmedchem.0c01245. Epub 2020 Nov 30. J Med Chem. 2020. PMID: 33252239
Optimal network sizes for most robust Turing patterns.
Shaberi HSA, Kappassov A, Matas-Gil A, Endres RG. Shaberi HSA, et al. Among authors: endres rg. Sci Rep. 2025 Jan 23;15(1):2948. doi: 10.1038/s41598-025-86854-7. Sci Rep. 2025. PMID: 39849094 Free article.
A three-node Turing gene circuit forms periodic spatial patterns in bacteria.
Tica J, Oliver Huidobro M, Zhu T, Wachter GKA, Pazuki RH, Bazzoli DG, Scholes NS, Tonello E, Siebert H, Stumpf MPH, Endres RG, Isalan M. Tica J, et al. Among authors: endres rg. Cell Syst. 2024 Dec 18;15(12):1123-1132.e3. doi: 10.1016/j.cels.2024.11.002. Epub 2024 Dec 2. Cell Syst. 2024. PMID: 39626670 Free article.
Therapeutic stance towards persons with psychosis - a Grounded Theory study.
Galbusera L, Endres R, Scholz T, Jirku E, Thoma S. Galbusera L, et al. Among authors: endres r. Int J Qual Stud Health Well-being. 2024 Dec;19(1):2333064. doi: 10.1080/17482631.2024.2333064. Epub 2024 Mar 29. Int J Qual Stud Health Well-being. 2024. PMID: 38552196 Free PMC article.
169 results