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Dimer Organization of Membrane-Associated NS5A of Hepatitis C Virus as Determined by Highly Sensitive 1 H-Detected Solid-State NMR.
Jirasko V, Lends A, Lakomek NA, Fogeron ML, Weber ME, Malär AA, Penzel S, Bartenschlager R, Meier BH, Böckmann A. Jirasko V, et al. Among authors: bartenschlager r. Angew Chem Int Ed Engl. 2021 Mar 1;60(10):5339-5347. doi: 10.1002/anie.202013296. Epub 2021 Jan 18. Angew Chem Int Ed Engl. 2021. PMID: 33205864 Free PMC article.
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment.
Reiss S, Rebhan I, Backes P, Romero-Brey I, Erfle H, Matula P, Kaderali L, Poenisch M, Blankenburg H, Hiet MS, Longerich T, Diehl S, Ramirez F, Balla T, Rohr K, Kaul A, Bühler S, Pepperkok R, Lengauer T, Albrecht M, Eils R, Schirmacher P, Lohmann V, Bartenschlager R. Reiss S, et al. Among authors: bartenschlager r. Cell Host Microbe. 2011 Jan 20;9(1):32-45. doi: 10.1016/j.chom.2010.12.002. Cell Host Microbe. 2011. PMID: 21238945 Free PMC article.
Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication.
Berger C, Romero-Brey I, Radujkovic D, Terreux R, Zayas M, Paul D, Harak C, Hoppe S, Gao M, Penin F, Lohmann V, Bartenschlager R. Berger C, et al. Among authors: bartenschlager r. Gastroenterology. 2014 Nov;147(5):1094-105.e25. doi: 10.1053/j.gastro.2014.07.019. Epub 2014 Jul 18. Gastroenterology. 2014. PMID: 25046163 Free article.
Wheat germ cell-free expression: Two detergents with a low critical micelle concentration allow for production of soluble HCV membrane proteins.
Fogeron ML, Badillo A, Jirasko V, Gouttenoire J, Paul D, Lancien L, Moradpour D, Bartenschlager R, Meier BH, Penin F, Böckmann A. Fogeron ML, et al. Among authors: bartenschlager r. Protein Expr Purif. 2015 Jan;105:39-46. doi: 10.1016/j.pep.2014.10.003. Epub 2014 Oct 12. Protein Expr Purif. 2015. PMID: 25306874
443 results