Verdin E - Search Results

1

Senescent cells promote tissue NAD⁺ decline during ageing via the activation of CD38⁺ macrophages.

Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin KO, Lee YM, Riley R, Ben-Sahra I, Ott M, Schilling B, Scheibye-Knudsen M, Ishihara K, Quake SR, Newman J, Brenner C, Campisi J, Verdin E. Covarrubias AJ, et al. Among authors: verdin e. Nat Metab. 2020 Nov;2(11):1265-1283. doi: 10.1038/s42255-020-00305-3. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199924 Free PMC article.

2

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase.

Schwer B, North BJ, Frye RA, Ott M, Verdin E. Schwer B, et al. Among authors: verdin e. J Cell Biol. 2002 Aug 19;158(4):647-57. doi: 10.1083/jcb.200205057. Epub 2002 Aug 19. J Cell Biol. 2002. PMID: 12186850 Free PMC article.

3

Class II histone deacetylases: versatile regulators.

Verdin E, Dequiedt F, Kasler HG. Verdin E, et al. Trends Genet. 2003 May;19(5):286-93. doi: 10.1016/S0168-9525(03)00073-8. Trends Genet. 2003. PMID: 12711221 Free article. Review.

4

HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis.

Dequiedt F, Kasler H, Fischle W, Kiermer V, Weinstein M, Herndier BG, Verdin E. Dequiedt F, et al. Among authors: verdin e. Immunity. 2003 May;18(5):687-98. doi: 10.1016/s1074-7613(03)00109-2. Immunity. 2003. PMID: 12753745 Free article.

5

Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation.

Parra M, Kasler H, McKinsey TA, Olson EN, Verdin E. Parra M, et al. Among authors: verdin e. J Biol Chem. 2005 Apr 8;280(14):13762-70. doi: 10.1074/jbc.M413396200. Epub 2004 Dec 28. J Biol Chem. 2005. PMID: 15623513 Free article.

6

The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter.

Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E. Mahmoudi T, et al. Among authors: verdin e. J Biol Chem. 2006 Jul 21;281(29):19960-8. doi: 10.1074/jbc.M603336200. Epub 2006 May 10. J Biol Chem. 2006. PMID: 16687403 Free article.

7

Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes.

Kasler HG, Verdin E. Kasler HG, et al. Among authors: verdin e. Mol Cell Biol. 2007 Jul;27(14):5184-200. doi: 10.1128/MCB.02091-06. Epub 2007 Apr 30. Mol Cell Biol. 2007. PMID: 17470548 Free PMC article.

8

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.

Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV Jr, Alt FW, Kahn CR, Verdin E. Hirschey MD, et al. Among authors: verdin e. Nature. 2010 Mar 4;464(7285):121-5. doi: 10.1038/nature08778. Nature. 2010. PMID: 20203611 Free PMC article.

9

The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription.

Pagans S, Kauder SE, Kaehlcke K, Sakane N, Schroeder S, Dormeyer W, Trievel RC, Verdin E, Schnolzer M, Ott M. Pagans S, et al. Among authors: verdin e. Cell Host Microbe. 2010 Mar 18;7(3):234-44. doi: 10.1016/j.chom.2010.02.005. Cell Host Microbe. 2010. PMID: 20227666 Free PMC article.

10

HAT trick: p300, small molecule, inhibitor.

Ott M, Verdin E. Ott M, et al. Among authors: verdin e. Chem Biol. 2010 May 28;17(5):417-8. doi: 10.1016/j.chembiol.2010.05.002. Chem Biol. 2010. PMID: 20534339

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