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Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain.
Carino A, Moraca F, Fiorillo B, Marchianò S, Sepe V, Biagioli M, Finamore C, Bozza S, Francisci D, Distrutti E, Catalanotti B, Zampella A, Fiorucci S. Carino A, et al. Among authors: moraca f. Front Chem. 2020 Oct 23;8:572885. doi: 10.3389/fchem.2020.572885. eCollection 2020. Front Chem. 2020. PMID: 33195060 Free PMC article.
Targeting multiple G-quadruplex-forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives.
Catalano R, Moraca F, Amato J, Cristofari C, Rigo R, Via LD, Rocca R, Lupia A, Maruca A, Costa G, Catalanotti B, Artese A, Pagano B, Randazzo A, Sissi C, Novellino E, Alcaro S. Catalano R, et al. Among authors: moraca f. Eur J Med Chem. 2019 Nov 15;182:111627. doi: 10.1016/j.ejmech.2019.111627. Epub 2019 Aug 16. Eur J Med Chem. 2019. PMID: 31446246
Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents.
Deplano A, Karlsson J, Moraca F, Svensson M, Cristiano C, Morgillo CM, Fowler CJ, Russo R, Catalanotti B, Onnis V. Deplano A, et al. Among authors: moraca f. J Enzyme Inhib Med Chem. 2021 Dec;36(1):940-953. doi: 10.1080/14756366.2021.1875459. J Enzyme Inhib Med Chem. 2021. PMID: 33896320 Free PMC article.
The TBC1D31/praja2 complex controls primary ciliogenesis through PKA-directed OFD1 ubiquitylation.
Senatore E, Chiuso F, Rinaldi L, Intartaglia D, Delle Donne R, Pedone E, Catalanotti B, Pirone L, Fiorillo B, Moraca F, Giamundo G, Scala G, Raffeiner A, Torres-Quesada O, Stefan E, Kwiatkowski M, van Pijkeren A, Morleo M, Franco B, Garbi C, Conte I, Feliciello A. Senatore E, et al. Among authors: moraca f. EMBO J. 2021 May 17;40(10):e106503. doi: 10.15252/embj.2020106503. Epub 2021 May 2. EMBO J. 2021. PMID: 33934390 Free PMC article.
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma.
Di Giorgio C, Lupia A, Marchianò S, Bordoni M, Bellini R, Massa C, Urbani G, Roselli R, Moraca F, Sepe V, Catalanotti B, Morretta E, Monti MC, Biagioli M, Distrutti E, Zampella A, Fiorucci S. Di Giorgio C, et al. Among authors: moraca f. Cells. 2022 Nov 3;11(21):3482. doi: 10.3390/cells11213482. Cells. 2022. PMID: 36359879 Free PMC article.
Molecular Basis for Non-Covalent, Non-Competitive FAAH Inhibition.
Morgillo CM, Lupia A, Deplano A, Pirone L, Fiorillo B, Pedone E, Luque FJ, Onnis V, Moraca F, Catalanotti B. Morgillo CM, et al. Among authors: moraca f. Int J Mol Sci. 2022 Dec 7;23(24):15502. doi: 10.3390/ijms232415502. Int J Mol Sci. 2022. PMID: 36555144 Free PMC article.
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