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An automated, highly sensitive LC-MS/MS assay for the quantification of the opiate antagonist naltrexone and its major metabolite 6beta-naltrexol in dog and human plasma.
Clavijo C, Bendrick-Peart J, Zhang YL, Johnson G, Gasparic A, Christians U. Clavijo C, et al. Among authors: christians u. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Oct 15;874(1-2):33-41. doi: 10.1016/j.jchromb.2008.08.021. Epub 2008 Sep 5. J Chromatogr B Analyt Technol Biomed Life Sci. 2008. PMID: 18805072
Development and validation of a semi-automated assay for the highly sensitive quantification of Biolimus A9 in human whole blood using high-performance liquid chromatography-tandem mass spectrometry.
Clavijo C, Strom T, Moll V, Betts R, Zhang YL, Christians U, Bendrick-Peart J. Clavijo C, et al. Among authors: christians u. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Nov 1;877(29):3506-14. doi: 10.1016/j.jchromb.2009.08.020. Epub 2009 Aug 21. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19762292 Free PMC article.
Randomized, double-blind, placebo-controlled, single intravenous dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of the novel coronary smooth muscle cell proliferation inhibitor Biolimus A9 in healthy individuals.
Steudel W, Dingmann C, Zhang YL, Bendrick-Peart J, Clavijo C, Shulze J, Betts R, Christians U. Steudel W, et al. Among authors: christians u. J Clin Pharmacol. 2011 Jan;51(1):29-39. doi: 10.1177/0091270010361255. Epub 2010 Mar 19. J Clin Pharmacol. 2011. PMID: 20305057 Clinical Trial.
A sensitive assay for the quantification of morphine and its active metabolites in human plasma and dried blood spots using high-performance liquid chromatography-tandem mass spectrometry.
Clavijo CF, Hoffman KL, Thomas JJ, Carvalho B, Chu LF, Drover DR, Hammer GB, Christians U, Galinkin JL. Clavijo CF, et al. Among authors: christians u. Anal Bioanal Chem. 2011 May;400(3):715-28. doi: 10.1007/s00216-011-4775-z. Epub 2011 Mar 12. Anal Bioanal Chem. 2011. PMID: 21400080
348 results