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261 results

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Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations.
Gollins S, West N, Sebag-Montefiore D, Myint AS, Saunders M, Susnerwala S, Quirke P, Essapen S, Samuel L, Sizer B, Worlding J, Southward K, Hemmings G, Tinkler-Hundal E, Taylor M, Bottomley D, Chambers P, Lawrie E, Lopes A, Beare S. Gollins S, et al. Br J Cancer. 2017 Oct 24;117(9):1286-1294. doi: 10.1038/bjc.2017.294. Epub 2017 Aug 31. Br J Cancer. 2017. PMID: 28859058 Free PMC article. Clinical Trial.
Differential and longitudinal immune gene patterns associated with reprogrammed microenvironment and viral mimicry in response to neoadjuvant radiotherapy in rectal cancer.
Wilkins A, Fontana E, Nyamundanda G, Ragulan C, Patil Y, Mansfield D, Kingston J, Errington-Mais F, Bottomley D, von Loga K, Bye H, Carter P, Tinkler-Hundal E, Noshirwani A, Downs J, Dillon M, Demaria S, Sebag-Montefiore D, Harrington K, West N, Melcher A, Sadanandam A. Wilkins A, et al. J Immunother Cancer. 2021 Mar;9(3):e001717. doi: 10.1136/jitc-2020-001717. J Immunother Cancer. 2021. PMID: 33678606 Free PMC article.
Associations between AI-Assisted Tumor Amphiregulin and Epiregulin IHC and Outcomes from Anti-EGFR Therapy in the Routine Management of Metastatic Colorectal Cancer.
Williams CJM, Elliott F, Sapanara N, Aghaei F, Zhang L, Muranyi A, Yan D, Bai I, Zhao Z, Shires M, Wood HM, Richman SD, Hemmings G, Hale M, Bottomley D, Galvin L, Cartlidge C, Dance S, Bacon CM, Mansfield L, Young-Zvandasara K, Sudan A, Lambert K, Bibby I, Coupland SE, Montazeri A, Kipling N, Hughes K, Cross SS, Dewdney A, Pheasey L, Leng C, Gochera T, Mangham DC, Saunders M, Pritchard M, Stott H, Mukherjee A, Ilyas M, Silverman R, Hyland G, Sculthorpe D, Thornton K, Gould I, O'Callaghan A, Brown N, Turnbull S, Shaw L, Seymour MT, West NP, Seligmann JF, Singh S, Shanmugam K, Quirke P. Williams CJM, et al. Among authors: west np. Clin Cancer Res. 2023 Oct 13;29(20):4153-4165. doi: 10.1158/1078-0432.CCR-23-0859. Clin Cancer Res. 2023. PMID: 37363997 Free PMC article.
The ATOM-Seq sequence capture panel can accurately predict microsatellite instability status in formalin-fixed tumour samples, alongside routine gene mutation testing.
Srihar K, Gusnanto A, Richman SD, West NP, Galvin L, Bottomley D, Hemmings G, Glover A, Natarajan S, Miller R, Arif S, Rossington H, Dunwell TL, Dailey SC, Fontarum G, George A, Wu W, Quirke P, Wood HM. Srihar K, et al. Among authors: west np. Sci Rep. 2024 Sep 19;14(1):21870. doi: 10.1038/s41598-024-72419-7. Sci Rep. 2024. PMID: 39300198 Free PMC article.
261 results