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Regulatory T cells engineered with TCR signaling-responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter.
Eskandari SK, Sulkaj I, Melo MB, Li N, Allos H, Alhaddad JB, Kollar B, Borges TJ, Eskandari AS, Zinter MA, Cai S, Assaker JP, Choi JY, Al Dulaijan BS, Mansouri A, Haik Y, Tannous BA, van Son WJ, Leuvenink HGD, Pomahac B, Riella LV, Tang L, Seelen MAJ, Irvine DJ, Azzi JR. Eskandari SK, et al. Among authors: tang l. Sci Transl Med. 2020 Nov 11;12(569):eaaw4744. doi: 10.1126/scitranslmed.aaw4744. Sci Transl Med. 2020. PMID: 33177180 Free PMC article.
Biomaterial Strategies for Immunomodulation.
Hotaling NA, Tang L, Irvine DJ, Babensee JE. Hotaling NA, et al. Among authors: tang l. Annu Rev Biomed Eng. 2015;17:317-49. doi: 10.1146/annurev-bioeng-071813-104814. Epub 2015 Sep 29. Annu Rev Biomed Eng. 2015. PMID: 26421896 Free PMC article. Review.
Donor cell engineering with GSK3 inhibitor-loaded nanoparticles enhances engraftment after in utero transplantation.
Loukogeorgakis SP, Fachin CG, Dias AIBS, Li H, Tang L, Kim AG, Vrecenak JD, Stratigis JD, Ahn NJ, Nissim I, Nissim I, Moron AF, Martins JL, Peranteau WH, De Coppi P, Irvine DJ, Flake AW. Loukogeorgakis SP, et al. Among authors: tang l. Blood. 2019 Nov 28;134(22):1983-1995. doi: 10.1182/blood.2019001037. Blood. 2019. PMID: 31570489 Free article.
Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity.
Guo Y, Xie YQ, Gao M, Zhao Y, Franco F, Wenes M, Siddiqui I, Bevilacqua A, Wang H, Yang H, Feng B, Xie X, Sabatel CM, Tschumi B, Chaiboonchoe A, Wang Y, Li W, Xiao W, Held W, Romero P, Ho PC, Tang L. Guo Y, et al. Among authors: tang l. Nat Immunol. 2021 Jun;22(6):746-756. doi: 10.1038/s41590-021-00940-2. Epub 2021 May 24. Nat Immunol. 2021. PMID: 34031618 Free PMC article.
Microfluidic T Cell Selection by Cellular Avidity.
Ashby JF, Schmidt J, Kc N, Kurum A, Koch C, Harari A, Tang L, Au SH. Ashby JF, et al. Among authors: tang l. Adv Healthc Mater. 2022 Aug;11(16):e2200169. doi: 10.1002/adhm.202200169. Epub 2022 Jun 21. Adv Healthc Mater. 2022. PMID: 35657072 Free PMC article.
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