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Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm.
Doyle SR, Tracey A, Laing R, Holroyd N, Bartley D, Bazant W, Beasley H, Beech R, Britton C, Brooks K, Chaudhry U, Maitland K, Martinelli A, Noonan JD, Paulini M, Quail MA, Redman E, Rodgers FH, Sallé G, Shabbir MZ, Sankaranarayanan G, Wit J, Howe KL, Sargison N, Devaney E, Berriman M, Gilleard JS, Cotton JA. Doyle SR, et al. Among authors: martinelli a. Commun Biol. 2020 Nov 9;3(1):656. doi: 10.1038/s42003-020-01377-3. Commun Biol. 2020. PMID: 33168940 Free PMC article.
Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus.
Doyle SR, Illingworth CJR, Laing R, Bartley DJ, Redman E, Martinelli A, Holroyd N, Morrison AA, Rezansoff A, Tracey A, Devaney E, Berriman M, Sargison N, Cotton JA, Gilleard JS. Doyle SR, et al. Among authors: martinelli a. BMC Genomics. 2019 Mar 15;20(1):218. doi: 10.1186/s12864-019-5592-6. BMC Genomics. 2019. PMID: 30876405 Free PMC article.
The confounding effects of high genetic diversity on the determination and interpretation of differential gene expression analysis in the parasitic nematode Haemonchus contortus.
Rezansoff AM, Laing R, Martinelli A, Stasiuk S, Redman E, Bartley D, Holroyd N, Devaney E, Sargison ND, Doyle S, Cotton JA, Gilleard JS. Rezansoff AM, et al. Among authors: martinelli a. Int J Parasitol. 2019 Oct;49(11):847-858. doi: 10.1016/j.ijpara.2019.05.012. Epub 2019 Sep 13. Int J Parasitol. 2019. PMID: 31525371 Free article.
The cytochrome P450 family in the parasitic nematode Haemonchus contortus.
Laing R, Bartley DJ, Morrison AA, Rezansoff A, Martinelli A, Laing ST, Gilleard JS. Laing R, et al. Among authors: martinelli a. Int J Parasitol. 2015 Mar;45(4):243-51. doi: 10.1016/j.ijpara.2014.12.001. Epub 2014 Dec 31. Int J Parasitol. 2015. PMID: 25558056 Free PMC article.
The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery.
Laing R, Kikuchi T, Martinelli A, Tsai IJ, Beech RN, Redman E, Holroyd N, Bartley DJ, Beasley H, Britton C, Curran D, Devaney E, Gilabert A, Hunt M, Jackson F, Johnston SL, Kryukov I, Li K, Morrison AA, Reid AJ, Sargison N, Saunders GI, Wasmuth JD, Wolstenholme A, Berriman M, Gilleard JS, Cotton JA. Laing R, et al. Among authors: martinelli a. Genome Biol. 2013 Aug 28;14(8):R88. doi: 10.1186/gb-2013-14-8-r88. Genome Biol. 2013. PMID: 23985316 Free PMC article.
Increased Expression of a MicroRNA Correlates with Anthelmintic Resistance in Parasitic Nematodes.
Gillan V, Maitland K, Laing R, Gu H, Marks ND, Winter AD, Bartley D, Morrison A, Skuce PJ, Rezansoff AM, Gilleard JS, Martinelli A, Britton C, Devaney E. Gillan V, et al. Among authors: martinelli a. Front Cell Infect Microbiol. 2017 Nov 6;7:452. doi: 10.3389/fcimb.2017.00452. eCollection 2017. Front Cell Infect Microbiol. 2017. PMID: 29209592 Free PMC article.
Transcriptomic profiling of nematode parasites surviving vaccine exposure.
Sallé G, Laing R, Cotton JA, Maitland K, Martinelli A, Holroyd N, Tracey A, Berriman M, Smith WD, Newlands GFJ, Hanks E, Devaney E, Britton C. Sallé G, et al. Among authors: martinelli a. Int J Parasitol. 2018 Apr;48(5):395-402. doi: 10.1016/j.ijpara.2018.01.004. Epub 2018 Mar 10. Int J Parasitol. 2018. PMID: 29534987 Free PMC article.
Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites.
Hunt P, Martinelli A, Modrzynska K, Borges S, Creasey A, Rodrigues L, Beraldi D, Loewe L, Fawcett R, Kumar S, Thomson M, Trivedi U, Otto TD, Pain A, Blaxter M, Cravo P. Hunt P, et al. Among authors: martinelli a. BMC Genomics. 2010 Sep 16;11:499. doi: 10.1186/1471-2164-11-499. BMC Genomics. 2010. PMID: 20846421 Free PMC article.
810 results