Castro J - Search Results

1

c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder.

Contreras PS, Tapia PJ, González-Hódar L, Peluso I, Soldati C, Napolitano G, Matarese M, Heras ML, Valls C, Martinez A, Balboa E, Castro J, Leal N, Platt FM, Sobota A, Winter D, Klein AD, Medina DL, Ballabio A, Alvarez AR, Zanlungo S. Contreras PS, et al. Among authors: castro j. iScience. 2020 Oct 15;23(11):101691. doi: 10.1016/j.isci.2020.101691. eCollection 2020 Nov 20. iScience. 2020. PMID: 33163944 Free PMC article.

2

Lysosomal vitamin E accumulation in Niemann-Pick type C disease.

Yévenes LF, Klein A, Castro JF, Marín T, Leal N, Leighton F, Alvarez AR, Zanlungo S. Yévenes LF, et al. Biochim Biophys Acta. 2012 Feb;1822(2):150-60. doi: 10.1016/j.bbadis.2011.11.009. Epub 2011 Nov 15. Biochim Biophys Acta. 2012. PMID: 22120593 Free article.

3

Genistein Activates Transcription Factor EB and Corrects Niemann-Pick C Phenotype.

Argüello G, Balboa E, Tapia PJ, Castro J, Yañez MJ, Mattar P, Pulgar R, Zanlungo S. Argüello G, et al. Among authors: castro j. Int J Mol Sci. 2021 Apr 19;22(8):4220. doi: 10.3390/ijms22084220. Int J Mol Sci. 2021. PMID: 33921734 Free PMC article.

4

Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C mice.

Marín T, Contreras P, Castro JF, Chamorro D, Balboa E, Bosch-Morató M, Muñoz FJ, Alvarez AR, Zanlungo S. Marín T, et al. Among authors: castro jf. Nutrients. 2014 Jul 30;6(8):3000-17. doi: 10.3390/nu6083000. Nutrients. 2014. PMID: 25079853 Free PMC article.

5

Disruption in connexin-based communication is associated with intracellular Ca²⁺ signal alterations in astrocytes from Niemann-Pick type C mice.

Sáez PJ, Orellana JA, Vega-Riveros N, Figueroa VA, Hernández DE, Castro JF, Klein AD, Jiang JX, Zanlungo S, Sáez JC. Sáez PJ, et al. Among authors: castro jf. PLoS One. 2013 Aug 15;8(8):e71361. doi: 10.1371/journal.pone.0071361. eCollection 2013. PLoS One. 2013. PMID: 23977027 Free PMC article.

6

Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease.

Alvarez AR, Klein A, Castro J, Cancino GI, Amigo J, Mosqueira M, Vargas LM, Yévenes LF, Bronfman FC, Zanlungo S. Alvarez AR, et al. Among authors: castro j. FASEB J. 2008 Oct;22(10):3617-27. doi: 10.1096/fj.07-102715. Epub 2008 Jun 30. FASEB J. 2008. PMID: 18591368

7

Deficiency of Niemann-Pick C1 protein protects against diet-induced gallstone formation in mice.

Morales MG, Amigo L, Balboa E, Acuña M, Castro J, Molina H, Miquel JF, Nervi F, Rigotti A, Zanlungo S. Morales MG, et al. Among authors: castro j. Liver Int. 2010 Jul;30(6):887-97. doi: 10.1111/j.1478-3231.2010.02230.x. Epub 2010 Apr 8. Liver Int. 2010. PMID: 20408952

8

Npc1 deficiency in the C57BL/6J genetic background enhances Niemann-Pick disease type C spleen pathology.

Parra J, Klein AD, Castro J, Morales MG, Mosqueira M, Valencia I, Cortés V, Rigotti A, Zanlungo S. Parra J, et al. Among authors: castro j. Biochem Biophys Res Commun. 2011 Sep 30;413(3):400-6. doi: 10.1016/j.bbrc.2011.08.096. Epub 2011 Sep 2. Biochem Biophys Res Commun. 2011. PMID: 21910975

9

Niemann-Pick C2 protein expression regulates lithogenic diet-induced gallstone formation and dietary cholesterol metabolism in mice.

Balboa E, Morales G, Aylwin P, Carrasco G, Amigo L, Castro J, Rigotti A, Zanlungo S. Balboa E, et al. Among authors: castro j. Lipids. 2012 Jan;47(1):13-25. doi: 10.1007/s11745-011-3625-2. Epub 2011 Oct 30. Lipids. 2012. PMID: 22038687

10

Transgenic overexpression of Niemann-Pick C2 protein promotes cholesterol gallstone formation in mice.

Acuña M, González-Hódar L, Amigo L, Castro J, Morales MG, Cancino GI, Groen AK, Young J, Miquel JF, Zanlungo S. Acuña M, et al. Among authors: castro j. J Hepatol. 2016 Feb;64(2):361-369. doi: 10.1016/j.jhep.2015.10.002. Epub 2015 Dec 10. J Hepatol. 2016. PMID: 26453970

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