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Transient Treg depletion enhances therapeutic anti-cancer vaccination.
Fisher SA, Aston WJ, Chee J, Khong A, Cleaver AL, Solin JN, Ma S, Lesterhuis WJ, Dick I, Holt RA, Creaney J, Boon L, Robinson B, Lake RA. Fisher SA, et al. Among authors: holt ra. Immun Inflamm Dis. 2016 Nov 21;5(1):16-28. doi: 10.1002/iid3.136. eCollection 2017 Mar. Immun Inflamm Dis. 2016. PMID: 28250921 Free PMC article.
Genome and Transcriptome Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors.
Pender A, Titmuss E, Pleasance ED, Fan KY, Pearson H, Brown SD, Grisdale CJ, Topham JT, Shen Y, Bonakdar M, Taylor GA, Williamson LM, Mungall KL, Chuah E, Mungall AJ, Moore RA, Lavoie JM, Yip S, Lim H, Renouf DJ, Sun S, Holt RA, Jones SJM, Marra MA, Laskin J. Pender A, et al. Among authors: holt ra. Clin Cancer Res. 2021 Jan 1;27(1):202-212. doi: 10.1158/1078-0432.CCR-20-1163. Epub 2020 Oct 5. Clin Cancer Res. 2021. PMID: 33020056 Clinical Trial.
Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy.
Principe N, Kidman J, Goh S, Tilsed CM, Fisher SA, Fear VS, Forbes CA, Zemek RM, Chopra A, Watson M, Dick IM, Boon L, Holt RA, Lake RA, Nowak AK, Lesterhuis WJ, McDonnell AM, Chee J. Principe N, et al. Among authors: holt ra. Front Immunol. 2020 Nov 12;11:584423. doi: 10.3389/fimmu.2020.584423. eCollection 2020. Front Immunol. 2020. PMID: 33262762 Free PMC article.
Profiling model T-cell metagenomes with short reads.
Warren RL, Nelson BH, Holt RA. Warren RL, et al. Among authors: holt ra. Bioinformatics. 2009 Feb 15;25(4):458-64. doi: 10.1093/bioinformatics/btp010. Epub 2009 Jan 9. Bioinformatics. 2009. PMID: 19136549
T-cell epitope discovery technologies.
Sharma G, Holt RA. Sharma G, et al. Among authors: holt ra. Hum Immunol. 2014 Jun;75(6):514-9. doi: 10.1016/j.humimm.2014.03.003. Epub 2014 Apr 19. Hum Immunol. 2014. PMID: 24755351 Review.
275 results