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The role of Hippo-YAP signaling in squamous cell carcinomas.
Maehama T, Nishio M, Otani J, Mak TW, Suzuki A. Maehama T, et al. Among authors: otani j. Cancer Sci. 2021 Jan;112(1):51-60. doi: 10.1111/cas.14725. Epub 2020 Dec 9. Cancer Sci. 2021. PMID: 33159406 Free PMC article. Review.
Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency.
Nishio M, Miyachi Y, Otani J, Tane S, Omori H, Ueda F, Togashi H, Sasaki T, Mak TW, Nakao K, Fujita Y, Nishina H, Maehama T, Suzuki A. Nishio M, et al. Among authors: otani j. FASEB J. 2019 Apr;33(4):5548-5560. doi: 10.1096/fj.201802005R. Epub 2019 Jan 14. FASEB J. 2019. PMID: 30640535
Our data show that YAP1 activation controls cell competition in part by decreasing cell adhesion.-Nishio, M., Miyachi, Y., Otani, J., Tane, S., Omori, H., Ueda, F., Togashi, H., Sasaki, T., Mak, T. W., Nakao, K., Fujita, Y., Nishina, H., Maehama, T., Suzuki, A. ...
Our data show that YAP1 activation controls cell competition in part by decreasing cell adhesion.-Nishio, M., Miyachi, Y., Otani, …
Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice.
Nishio M, To Y, Maehama T, Aono Y, Otani J, Hikasa H, Kitagawa A, Mimori K, Sasaki T, Nishina H, Toyokuni S, Lydon JP, Nakao K, Wah Mak T, Kiyono T, Katabuchi H, Tashiro H, Suzuki A. Nishio M, et al. Among authors: otani j. Cancer Sci. 2020 Oct;111(10):3576-3587. doi: 10.1111/cas.14581. Epub 2020 Aug 21. Cancer Sci. 2020. PMID: 32716083 Free PMC article.
Alantolactone is a natural product that potently inhibits YAP1/TAZ through promotion of reactive oxygen species accumulation.
Nakatani K, Maehama T, Nishio M, Otani J, Yamaguchi K, Fukumoto M, Hikasa H, Hagiwara S, Nishina H, Mak TW, Honma T, Kondoh Y, Osada H, Yoshida M, Suzuki A. Nakatani K, et al. Among authors: otani j. Cancer Sci. 2021 Oct;112(10):4303-4316. doi: 10.1111/cas.15079. Epub 2021 Aug 6. Cancer Sci. 2021. PMID: 34289205 Free PMC article.
Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers.
Soyama H, Nishio M, Otani J, Sakuma T, Takao S, Hara S, Masuda T, Mimori K, Toyokuni S, Lydon JP, Nakao K, Nishina H, Fukumoto T, Maehama T, Suzuki A. Soyama H, et al. Among authors: otani j. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2123134119. doi: 10.1073/pnas.2123134119. Epub 2022 Jul 11. Proc Natl Acad Sci U S A. 2022. PMID: 35858357 Free PMC article.
Nucleolar stress: Molecular mechanisms and related human diseases.
Maehama T, Nishio M, Otani J, Mak TW, Suzuki A. Maehama T, et al. Among authors: otani j. Cancer Sci. 2023 May;114(5):2078-2086. doi: 10.1111/cas.15755. Epub 2023 Feb 28. Cancer Sci. 2023. PMID: 36762786 Free PMC article. Review.
Enhanced processivity of Dnmt1 by monoubiquitinated histone H3.
Mishima Y, Brueckner L, Takahashi S, Kawakami T, Otani J, Shinohara A, Takeshita K, Garvilles RG, Watanabe M, Sakai N, Takeshima H, Nachtegael C, Nishiyama A, Nakanishi M, Arita K, Nakashima K, Hojo H, Suetake I. Mishima Y, et al. Among authors: otani j. Genes Cells. 2020 Jan;25(1):22-32. doi: 10.1111/gtc.12732. Epub 2019 Dec 3. Genes Cells. 2020. PMID: 31680384 Free article.
61 results