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Page 1
EGFR + lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth.
Kuhlmann-Hogan A, Cordes T, Xu Z, Traina KA, Robles-Oteíza C, Ayeni D, Kwong EM, Levy SR, Nobari M, Cheng GZ, Shaw R, Leibel SL, Metallo CM, Politi K, Kaech SM. Kuhlmann-Hogan A, et al. Among authors: metallo cm. bioRxiv [Preprint]. 2023 Apr 17:2023.04.15.536974. doi: 10.1101/2023.04.15.536974. bioRxiv. 2023. Update in: Cancer Discov. 2024 Jan 19. doi: 10.1158/2159-8290.CD-23-0434 PMID: 37131637 Free PMC article. Updated. Preprint.
Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis.
Muta Y, Linares JF, Martinez-Ordoñez A, Duran A, Cid-Diaz T, Kinoshita H, Zhang X, Han Q, Nakanishi Y, Nakanishi N, Cordes T, Arora GK, Ruiz-Martinez M, Reina-Campos M, Kasashima H, Yashiro M, Maeda K, Albaladejo-Gonzalez A, Torres-Moreno D, García-Solano J, Conesa-Zamora P, Inghirami G, Metallo CM, Osborne TF, Diaz-Meco MT, Moscat J. Muta Y, et al. Among authors: metallo cm. Nat Commun. 2023 Dec 13;14(1):8075. doi: 10.1038/s41467-023-43690-5. Nat Commun. 2023. PMID: 38092754 Free PMC article.
EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth.
Kuhlmann-Hogan A, Cordes T, Xu Z, Kuna RS, Traina KA, Robles-Oteíza C, Ayeni D, Kwong EM, Levy S, Globig AM, Nobari MM, Cheng GZ, Leibel SL, Homer RJ, Shaw RJ, Metallo CM, Politi K, Kaech SM. Kuhlmann-Hogan A, et al. Among authors: metallo cm. Cancer Discov. 2024 Jan 25:OF1-OF22. doi: 10.1158/2159-8290.CD-23-0434. Online ahead of print. Cancer Discov. 2024. PMID: 38270272
IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism.
Grassian AR, Parker SJ, Davidson SM, Divakaruni AS, Green CR, Zhang X, Slocum KL, Pu M, Lin F, Vickers C, Joud-Caldwell C, Chung F, Yin H, Handly ED, Straub C, Growney JD, Vander Heiden MG, Murphy AN, Pagliarini R, Metallo CM. Grassian AR, et al. Among authors: metallo cm. Cancer Res. 2014 Jun 15;74(12):3317-31. doi: 10.1158/0008-5472.CAN-14-0772-T. Epub 2014 Apr 22. Cancer Res. 2014. PMID: 24755473 Free PMC article.
Regulation of substrate utilization by the mitochondrial pyruvate carrier.
Vacanti NM, Divakaruni AS, Green CR, Parker SJ, Henry RR, Ciaraldi TP, Murphy AN, Metallo CM. Vacanti NM, et al. Among authors: metallo cm. Mol Cell. 2014 Nov 6;56(3):425-435. doi: 10.1016/j.molcel.2014.09.024. Epub 2014 Oct 30. Mol Cell. 2014. PMID: 25458843 Free PMC article.
137 results