Surewicz WK - Search Results

1

Small molecules as potent biphasic modulators of protein liquid-liquid phase separation.

Babinchak WM, Dumm BK, Venus S, Boyko S, Putnam AA, Jankowsky E, Surewicz WK. Babinchak WM, et al. Among authors: surewicz wk. Nat Commun. 2020 Nov 4;11(1):5574. doi: 10.1038/s41467-020-19211-z. Nat Commun. 2020. PMID: 33149109 Free PMC article.

2

Species-dependent structural polymorphism of Y145Stop prion protein amyloid revealed by solid-state NMR spectroscopy.

Theint T, Nadaud PS, Aucoin D, Helmus JJ, Pondaven SP, Surewicz K, Surewicz WK, Jaroniec CP. Theint T, et al. Among authors: surewicz wk, surewicz k. Nat Commun. 2017 Sep 29;8(1):753. doi: 10.1038/s41467-017-00794-z. Nat Commun. 2017. PMID: 28963458 Free PMC article.

3

The role of liquid-liquid phase separation in aggregation of the TDP-43 low-complexity domain.

Babinchak WM, Haider R, Dumm BK, Sarkar P, Surewicz K, Choi JK, Surewicz WK. Babinchak WM, et al. Among authors: surewicz wk, surewicz k. J Biol Chem. 2019 Apr 19;294(16):6306-6317. doi: 10.1074/jbc.RA118.007222. Epub 2019 Feb 27. J Biol Chem. 2019. PMID: 30814253 Free PMC article.

4

Liquid-liquid phase separation of tau protein: The crucial role of electrostatic interactions.

Boyko S, Qi X, Chen TH, Surewicz K, Surewicz WK. Boyko S, et al. Among authors: surewicz wk, surewicz k. J Biol Chem. 2019 Jul 19;294(29):11054-11059. doi: 10.1074/jbc.AC119.009198. Epub 2019 May 16. J Biol Chem. 2019. PMID: 31097543 Free PMC article.

5

Liquid-Liquid Phase Separation and Its Mechanistic Role in Pathological Protein Aggregation.

Babinchak WM, Surewicz WK. Babinchak WM, et al. Among authors: surewicz wk. J Mol Biol. 2020 Mar 27;432(7):1910-1925. doi: 10.1016/j.jmb.2020.03.004. Epub 2020 Mar 10. J Mol Biol. 2020. PMID: 32169484 Free PMC article. Review.

6

Zinc promotes liquid-liquid phase separation of tau protein.

Singh V, Xu L, Boyko S, Surewicz K, Surewicz WK. Singh V, et al. Among authors: surewicz wk, surewicz k. J Biol Chem. 2020 May 1;295(18):5850-5856. doi: 10.1074/jbc.AC120.013166. Epub 2020 Mar 30. J Biol Chem. 2020. PMID: 32229582 Free PMC article.

7

Studying Protein Aggregation in the Context of Liquid-liquid Phase Separation Using Fluorescence and Atomic Force Microscopy, Fluorescence and Turbidity Assays, and FRAP.

Babinchak WM, Surewicz WK. Babinchak WM, et al. Among authors: surewicz wk. Bio Protoc. 2020 Jan 20;10(2):e3489. doi: 10.21769/bioprotoc.3489. Bio Protoc. 2020. PMID: 32775538 Free PMC article.

8

Regulatory mechanisms of tau protein fibrillation under the conditions of liquid-liquid phase separation.

Boyko S, Surewicz K, Surewicz WK. Boyko S, et al. Among authors: surewicz wk, surewicz k. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31882-31890. doi: 10.1073/pnas.2012460117. Epub 2020 Dec 1. Proc Natl Acad Sci U S A. 2020. PMID: 33262278 Free PMC article.

9

Cryo-EM structure of amyloid fibrils formed by the entire low complexity domain of TDP-43.

Li Q, Babinchak WM, Surewicz WK. Li Q, et al. Among authors: surewicz wk. Nat Commun. 2021 Mar 12;12(1):1620. doi: 10.1038/s41467-021-21912-y. Nat Commun. 2021. PMID: 33712624 Free PMC article.

10

Tau liquid-liquid phase separation in neurodegenerative diseases.

Boyko S, Surewicz WK. Boyko S, et al. Among authors: surewicz wk. Trends Cell Biol. 2022 Jul;32(7):611-623. doi: 10.1016/j.tcb.2022.01.011. Epub 2022 Feb 15. Trends Cell Biol. 2022. PMID: 35181198 Free PMC article. Review.

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