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Novel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer.
Tailor D, Going CC, Resendez A, Kumar V, Nambiar DK, Li Y, Dheeraj A, LaGory EL, Ghoochani A, Birk AM, Stoyanova T, Ye J, Giaccia AJ, Le QT, Singh RP, Sledge GW, Pitteri SJ, Malhotra SV. Tailor D, et al. Among authors: giaccia aj. Br J Cancer. 2021 Feb;124(3):604-615. doi: 10.1038/s41416-020-01137-4. Epub 2020 Nov 3. Br J Cancer. 2021. PMID: 33139797 Free PMC article.
Hypoxic gene expression and metastasis.
Le QT, Denko NC, Giaccia AJ. Le QT, et al. Among authors: giaccia aj. Cancer Metastasis Rev. 2004 Aug-Dec;23(3-4):293-310. doi: 10.1023/B:CANC.0000031768.89246.d7. Cancer Metastasis Rev. 2004. PMID: 15197330 Review.
Long-range hypoxia signaling in NAFLD.
LaGory EL, Giaccia AJ. LaGory EL, et al. Among authors: giaccia aj. Nat Med. 2017 Nov 7;23(11):1251-1252. doi: 10.1038/nm.4436. Nat Med. 2017. PMID: 29117167 No abstract available.
Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4-pRB Axis in Fibroblasts at the Invasive Tumor Edge.
Bouchard G, Garcia-Marques FJ, Karacosta LG, Zhang W, Bermudez A, Riley NM, Varma S, Mehl LC, Benson JA, Shrager JB, Bertozzi CR, Pitteri SJ, Giaccia AJ, Plevritis SK. Bouchard G, et al. Among authors: giaccia aj. Cancer Res. 2022 Feb 15;82(4):648-664. doi: 10.1158/0008-5472.CAN-21-1705. Cancer Res. 2022. PMID: 34853070 Free PMC article.
Mitochondrial copper depletion suppresses triple-negative breast cancer in mice.
Cui L, Gouw AM, LaGory EL, Guo S, Attarwala N, Tang Y, Qi J, Chen YS, Gao Z, Casey KM, Bazhin AA, Chen M, Hu L, Xie J, Fang M, Zhang C, Zhu Q, Wang Z, Giaccia AJ, Gambhir SS, Zhu W, Felsher DW, Pegram MD, Goun EA, Le A, Rao J. Cui L, et al. Among authors: giaccia aj. Nat Biotechnol. 2021 Mar;39(3):357-367. doi: 10.1038/s41587-020-0707-9. Epub 2020 Oct 19. Nat Biotechnol. 2021. PMID: 33077961 Free PMC article.
344 results