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Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection.
Li W, Chen C, Drelich A, Martinez DR, Gralinski LE, Sun Z, Schäfer A, Kulkarni SS, Liu X, Leist SR, Zhelev DV, Zhang L, Kim YJ, Peterson EC, Conard A, Mellors JW, Tseng CK, Falzarano D, Baric RS, Dimitrov DS. Li W, et al. Among authors: dimitrov ds. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29832-29838. doi: 10.1073/pnas.2010197117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139569 Free PMC article.
Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies.
Zhu Z, Chakraborti S, He Y, Roberts A, Sheahan T, Xiao X, Hensley LE, Prabakaran P, Rockx B, Sidorov IA, Corti D, Vogel L, Feng Y, Kim JO, Wang LF, Baric R, Lanzavecchia A, Curtis KM, Nabel GJ, Subbarao K, Jiang S, Dimitrov DS. Zhu Z, et al. Among authors: dimitrov ds. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12123-8. doi: 10.1073/pnas.0701000104. Epub 2007 Jul 9. Proc Natl Acad Sci U S A. 2007. PMID: 17620608 Free PMC article.
Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets.
van Doremalen N, Falzarano D, Ying T, de Wit E, Bushmaker T, Feldmann F, Okumura A, Wang Y, Scott DP, Hanley PW, Feldmann H, Dimitrov DS, Munster VJ. van Doremalen N, et al. Among authors: dimitrov ds. Antiviral Res. 2017 Jul;143:30-37. doi: 10.1016/j.antiviral.2017.03.025. Epub 2017 Apr 5. Antiviral Res. 2017. PMID: 28389142 Free PMC article.
A defucosylated bispecific multivalent molecule exhibits broad HIV-1-neutralizing activity and enhanced antibody-dependent cellular cytotoxicity against reactivated HIV-1 latently infected cells.
Kong D, Wang Y, Ji P, Li W, Ying T, Huang J, Wang C, Wu Y, Wang Y, Chen W, Hao Y, Hong K, Shao Y, Dimitrov DS, Jiang S, Ma L. Kong D, et al. Among authors: dimitrov ds. AIDS. 2018 Aug 24;32(13):1749-1761. doi: 10.1097/QAD.0000000000001869. AIDS. 2018. PMID: 29762173
366 results