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Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors.
Mathew B, Srivastava S, Ross LJ, Suling WJ, White EL, Woolhiser LK, Lenaerts AJ, Reynolds RC. Mathew B, et al. Bioorg Med Chem. 2011 Dec 1;19(23):7120-8. doi: 10.1016/j.bmc.2011.09.062. Epub 2011 Oct 5. Bioorg Med Chem. 2011. PMID: 22024272 Free PMC article.
Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library.
Gibbons GS, Chakraborty A, Grigsby SM, Umeano AC, Liao C, Moukha-Chafiq O, Pathak V, Mathew B, Lee YT, Dou Y, Schürer SC, Reynolds RC, Snowden TS, Nikolovska-Coleska Z. Gibbons GS, et al. Among authors: mathew b. Eur J Med Chem. 2020 Mar 1;189:112023. doi: 10.1016/j.ejmech.2019.112023. Epub 2020 Jan 2. Eur J Med Chem. 2020. PMID: 31978781 Free PMC article.
Identification of Inhibitors of Thrombospondin 1 Activation of TGF-β.
Suto MJ, Gupta V, Mathew B, Zhang W, Pallero MA, Murphy-Ullrich JE. Suto MJ, et al. Among authors: mathew b. ACS Med Chem Lett. 2020 May 7;11(6):1130-1136. doi: 10.1021/acsmedchemlett.9b00540. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32550992 Free PMC article.
A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion.
Sharma J, Du M, Wong E, Mutyam V, Li Y, Chen J, Wangen J, Thrasher K, Fu L, Peng N, Tang L, Liu K, Mathew B, Bostwick RJ, Augelli-Szafran CE, Bihler H, Liang F, Mahiou J, Saltz J, Rab A, Hong J, Sorscher EJ, Mendenhall EM, Coppola CJ, Keeling KM, Green R, Mense M, Suto MJ, Rowe SM, Bedwell DM. Sharma J, et al. Among authors: mathew b. Nat Commun. 2021 Jul 16;12(1):4358. doi: 10.1038/s41467-021-24575-x. Nat Commun. 2021. PMID: 34272367 Free PMC article.
Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals.
Yatchang MF, Mathew B, Srivastava RK, Khan J, Muzaffar S, Zhang S, Wu M, Zhai L, Ruiz P, Agarwal A, Bostwick JR, Suto MJ, Athar M, Augelli-Szafran CE. Yatchang MF, et al. Among authors: mathew b. Bioorg Med Chem Lett. 2022 May 15;64:128696. doi: 10.1016/j.bmcl.2022.128696. Epub 2022 Mar 19. Bioorg Med Chem Lett. 2022. PMID: 35318165 Free PMC article.
Identification of Cytoprotective Small-Molecule Inducers of Heme-Oxygenase-1.
Ghajar-Rahimi G, Traylor AM, Mathew B, Bostwick JR, Nebane NM, Zmijewska AA, Esman SK, Thukral S, Zhai L, Sambandam V, Cowell RM, Suto MJ, George JF, Augelli-Szafran CE, Agarwal A. Ghajar-Rahimi G, et al. Among authors: mathew b. Antioxidants (Basel). 2022 Sep 23;11(10):1888. doi: 10.3390/antiox11101888. Antioxidants (Basel). 2022. PMID: 36290611 Free PMC article.
798 results