Cowell RM - Search Results

1

Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-ҡB activators for the treatment of ALS.

Mathew B, Ruiz P, Dutta S, Entrekin JT, Zhang S, Patel KD, Simmons MS, Augelli-Szafran CE, Cowell RM, Suto MJ. Mathew B, et al. Among authors: cowell rm. Eur J Med Chem. 2021 Jan 15;210:112952. doi: 10.1016/j.ejmech.2020.112952. Epub 2020 Oct 22. Eur J Med Chem. 2021. PMID: 33139114

2

McMeekin LJ, Joyce KL, Jenkins LM, Bohannon BM, Patel KD, Bohannon AS, Patel A, Fox SN, Simmons MS, Day JJ, Kralli A, Crossman DK, Cowell RM. McMeekin LJ, et al. Among authors: cowell rm. Neuroscience. 2021 Dec 15;479:70-90. doi: 10.1016/j.neuroscience.2021.10.007. Epub 2021 Oct 11. Neuroscience. 2021. PMID: 34648866 Free PMC article.

3

Corrigendum to "Estrogen-related Receptor Alpha (ERRα) is Required for PGC-1α-dependent Gene Expression in the Mouse Brain" [Neuroscience 479 (2021) 70-90].

McMeekin LJ, Joyce KL, Jenkins LM, Bohannon BM, Patel KD, Bohannon AS, Patel A, Fox SN, Simmons MS, Day JJ, Kralli A, Crossman DK, Cowell RM. McMeekin LJ, et al. Among authors: cowell rm. Neuroscience. 2022 Jun 15;493:119. doi: 10.1016/j.neuroscience.2022.05.011. Epub 2022 May 18. Neuroscience. 2022. PMID: 35594912 Free PMC article. No abstract available.

4

Fox SN, McMeekin LJ, Savage CH, Joyce KL, Boas SM, Simmons MS, Farmer CB, Ryan J, Pereboeva L, Becker K, Auwerx J, Sudarshan S, Ma J, Lee A, Roberts RC, Crossman DK, Kralli A, Cowell RM. Fox SN, et al. Among authors: cowell rm. NPJ Parkinsons Dis. 2022 Aug 18;8(1):106. doi: 10.1038/s41531-022-00369-w. NPJ Parkinsons Dis. 2022. PMID: 35982091 Free PMC article.

5

A Role for PGC-1α in Transcription and Excitability of Neocortical and Hippocampal Excitatory Neurons.

McMeekin LJ, Bartley AF, Bohannon AS, Adlaf EW, van Groen T, Boas SM, Fox SN, Detloff PJ, Crossman DK, Overstreet-Wadiche LS, Hablitz JJ, Dobrunz LE, Cowell RM. McMeekin LJ, et al. Among authors: cowell rm. Neuroscience. 2020 May 21;435:73-94. doi: 10.1016/j.neuroscience.2020.03.036. Epub 2020 Mar 25. Neuroscience. 2020. PMID: 32222555 Free PMC article.

6

PGC-1α provides a transcriptional framework for synchronous neurotransmitter release from parvalbumin-positive interneurons.

Lucas EK, Dougherty SE, McMeekin LJ, Reid CS, Dobrunz LE, West AB, Hablitz JJ, Cowell RM. Lucas EK, et al. Among authors: cowell rm. J Neurosci. 2014 Oct 22;34(43):14375-87. doi: 10.1523/JNEUROSCI.1222-14.2014. J Neurosci. 2014. PMID: 25339750 Free PMC article.

7

Cell-Specific Deletion of PGC-1α from Medium Spiny Neurons Causes Transcriptional Alterations and Age-Related Motor Impairment.

McMeekin LJ, Li Y, Fox SN, Rowe GC, Crossman DK, Day JJ, Li Y, Detloff PJ, Cowell RM. McMeekin LJ, et al. Among authors: cowell rm. J Neurosci. 2018 Mar 28;38(13):3273-3286. doi: 10.1523/JNEUROSCI.0848-17.2018. Epub 2018 Feb 28. J Neurosci. 2018. PMID: 29491012 Free PMC article.

8

Dysregulation of PGC-1α-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities.

McMeekin LJ, Fox SN, Boas SM, Cowell RM. McMeekin LJ, et al. Among authors: cowell rm. Cells. 2021 Feb 9;10(2):352. doi: 10.3390/cells10020352. Cells. 2021. PMID: 33572179 Free PMC article. Review.

9

Hyperactivity and cortical disinhibition in mice with restricted expression of mutant huntingtin to parvalbumin-positive cells.

Dougherty SE, Hollimon JJ, McMeekin LJ, Bohannon AS, West AB, Lesort M, Hablitz JJ, Cowell RM. Dougherty SE, et al. Among authors: cowell rm. Neurobiol Dis. 2014 Feb;62:160-71. doi: 10.1016/j.nbd.2013.10.002. Epub 2013 Oct 11. Neurobiol Dis. 2014. PMID: 24121117 Free PMC article.

10

Cerebellar transcriptional alterations with Purkinje cell dysfunction and loss in mice lacking PGC-1α.

Lucas EK, Reid CS, McMeekin LJ, Dougherty SE, Floyd CL, Cowell RM. Lucas EK, et al. Among authors: cowell rm. Front Cell Neurosci. 2015 Jan 6;8:441. doi: 10.3389/fncel.2014.00441. eCollection 2014. Front Cell Neurosci. 2015. PMID: 25610371 Free PMC article.

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