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The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Qing Ju Han, Han G, Peng J, Tang Z. Ai J, et al. Among authors: tesfaldet t. Free Radic Biol Med. 2021 Jan;162:181-190. doi: 10.1016/j.freeradbiomed.2020.10.003. Epub 2020 Oct 22. Free Radic Biol Med. 2021. PMID: 33131696
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Wang H, Ai J, Shopit A, Niu M, Ahmed N, Tesfaldet T, Tang Z, Li X, Jamalat Y, Chu P, Peng J, Ma X, Qaed E, Han G, Zhang W, Wang J, Tang Z. Wang H, et al. Among authors: tesfaldet t. Cell Biol Toxicol. 2022 Jun;38(3):531-551. doi: 10.1007/s10565-021-09644-7. Epub 2021 Aug 28. Cell Biol Toxicol. 2022. PMID: 34455488
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Han QJ, Han G, Peng J, Tang Z. Ai J, et al. Among authors: tesfaldet t. Free Radic Biol Med. 2022 Feb 1;179:416-417. doi: 10.1016/j.freeradbiomed.2021.12.306. Epub 2021 Dec 28. Free Radic Biol Med. 2022. PMID: 34972631 No abstract available.
miR-421 up-regulation by the oleanolic acid derivative K73-03 regulates epigenetically SPINK1 transcription in pancreatic cancer cells leading to metabolic changes and enhanced apoptosis.
Shopit A, Li X, Tang Z, Awsh M, Shobet L, Niu M, Wang H, Mousa H, Alshwmi M, Tesfaldet T, Gamallat Y, Li H, Chu P, Ahmad N, Jamalat Y, Ai J, Qaed E, Almoiliqy M, Wang S, Tang Z. Shopit A, et al. Among authors: tesfaldet t. Pharmacol Res. 2020 Nov;161:105130. doi: 10.1016/j.phrs.2020.105130. Epub 2020 Aug 17. Pharmacol Res. 2020. PMID: 32818653