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High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice.
Patel VS, Sitapara RA, Gore A, Phan B, Sharma L, Sampat V, Li JH, Yang H, Chavan SS, Wang H, Tracey KJ, Mantell LL. Patel VS, et al. Among authors: sitapara ra. Am J Respir Cell Mol Biol. 2013 Mar;48(3):280-7. doi: 10.1165/rcmb.2012-0279OC. Epub 2012 Oct 18. Am J Respir Cell Mol Biol. 2013. PMID: 23087050 Free PMC article.
Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury.
Entezari M, Javdan M, Antoine DJ, Morrow DM, Sitapara RA, Patel V, Wang M, Sharma L, Gorasiya S, Zur M, Wu W, Li J, Yang H, Ashby CR, Thomas D, Wang H, Mantell LL. Entezari M, et al. Among authors: sitapara ra. Redox Biol. 2014 Jan 20;2:314-22. doi: 10.1016/j.redox.2014.01.013. eCollection 2014. Redox Biol. 2014. PMID: 24563849 Free PMC article.
The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function.
Sitapara RA, Antoine DJ, Sharma L, Patel VS, Ashby CR Jr, Gorasiya S, Yang H, Zur M, Mantell LL. Sitapara RA, et al. Mol Med. 2014 Jun 19;20(1):238-47. doi: 10.2119/molmed.2013.00086. Mol Med. 2014. Retraction in: Mol Med. 2020 Dec 30;26(1):132. doi: 10.1186/s10020-020-00265-0 PMID: 24664237 Free PMC article. Retracted.
The compromise of macrophage functions by hyperoxia is attenuated by ethacrynic acid via inhibition of NF-κB-mediated release of high-mobility group box-1.
Wang M, Gorasiya S, Antoine DJ, Sitapara RA, Wu W, Sharma L, Yang H, Ashby CR Jr, Vasudevan D, Zur M, Thomas DD, Mantell LL. Wang M, et al. Among authors: sitapara ra. Am J Respir Cell Mol Biol. 2015 Feb;52(2):171-82. doi: 10.1165/rcmb.2013-0544OC. Am J Respir Cell Mol Biol. 2015. PMID: 24992505 Free PMC article.
The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation.
Sitapara RA, Gauthier AG, Valdés-Ferrer SI, Lin M, Patel V, Wang M, Martino AT, Perron JC, Ashby CR Jr, Tracey KJ, Pavlov VA, Mantell LL. Sitapara RA, et al. Mol Med. 2020 Jun 29;26(1):63. doi: 10.1186/s10020-020-00177-z. Mol Med. 2020. PMID: 32600307 Free PMC article.
15 results