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Lipopolysaccharide-induced sepsis-like state compromises post-ischemic neurological recovery, brain tissue survival and remodeling via mechanisms involving microvascular thrombosis and brain T cell infiltration.
Sardari M, Skuljec J, Yin D, Zec K, de Carvalho TS, Albers D, Wang C, Pul R, Popa-Wagner A, Doeppner TR, Kleinschnitz C, Dzyubenko E, Hermann DM. Sardari M, et al. Among authors: kleinschnitz c. Brain Behav Immun. 2021 Jan;91:627-638. doi: 10.1016/j.bbi.2020.10.015. Epub 2020 Oct 22. Brain Behav Immun. 2021. PMID: 33122024 Free article.
Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation.
Langhauser F, Göb E, Kraft P, Geis C, Schmitt J, Brede M, Göbel K, Helluy X, Pham M, Bendszus M, Jakob P, Stoll G, Meuth SG, Nieswandt B, McCrae KR, Kleinschnitz C. Langhauser F, et al. Among authors: kleinschnitz c. Blood. 2012 Nov 8;120(19):4082-92. doi: 10.1182/blood-2012-06-440057. Epub 2012 Aug 30. Blood. 2012. PMID: 22936662 Free PMC article.
Gain-of-function STAT1 mutations are associated with intracranial aneurysms.
Dadak M, Jacobs R, Skuljec J, Jirmo AC, Yildiz Ö, Donnerstag F, Baerlecken NT, Schmidt RE, Lanfermann H, Skripuletz T, Schwenkenbecher P, Kleinschnitz C, Tumani H, Stangel M, Pul R. Dadak M, et al. Among authors: kleinschnitz c. Clin Immunol. 2017 May;178:79-85. doi: 10.1016/j.clim.2017.01.012. Epub 2017 Feb 2. Clin Immunol. 2017. PMID: 28161409
Gute Ernährung reduziert MS-Symptome.
Pul R, Kleinschnitz C. Pul R, et al. Among authors: kleinschnitz c. MMW Fortschr Med. 2018 Oct;160(18):42. doi: 10.1007/s15006-018-1026-7. MMW Fortschr Med. 2018. PMID: 30350066 Review. German. No abstract available.
511 results