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Page 1
Reduced SLIT2 is Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in Acute Promyelocytic Leukemia.
Weinhäuser I, Pereira-Martins DA, Ortiz C, Silveira DR, Simões LAA, Bianco TM, Araujo CL, Koury LC, Melo RAM, Bittencourt RI, Pagnano K, Pasquini R, Nunes EC, Fagundes EM, Gloria AB, Kerbauy F, Chauffaille ML, Keating A, Tallman MS, Ribeiro RC, Dillon R, Ganser A, Löwenberg B, Valk P, Lo-Coco F, Sanz MA, Berliner N, Ammatuna E, Lucena-Araujo AR, Schuringa JJ, Rego EM. Weinhäuser I, et al. Among authors: schuringa jj. Cancers (Basel). 2020 Oct 27;12(11):3134. doi: 10.3390/cancers12113134. Cancers (Basel). 2020. PMID: 33120864 Free PMC article.
Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias.
Kwon MC, Thuring JW, Querolle O, Dai X, Verhulst T, Pande V, Marien A, Goffin D, Wenge DV, Yue H, Cutler JA, Jin C, Perner F, Hogeling SM, Shaffer PL, Jacobs F, Vinken P, Cai W, Keersmaekers V, Eyassu F, Bhogal B, Verstraeten K, El Ashkar S, Perry JA, Jayaguru P, Barreyro L, Kuchnio A, Darville N, Krosky D, Urbanietz G, Verbist B, Edwards JP, Cowley GS, Kirkpatrick R, Steele R, Ferrante L, Guttke C, Daskalakis N, Pietsch EC, Wilson DM, Attar R, Elsayed Y, Fischer ES, Schuringa JJ, Armstrong SA, Packman K, Philippar U. Kwon MC, et al. Among authors: schuringa jj. Blood. 2024 Sep 12;144(11):1206-1220. doi: 10.1182/blood.2023022480. Blood. 2024. PMID: 38905635 Free PMC article.
Pretransplantation MRD in Older Patients With AML After Treatment With Decitabine or Conventional Chemotherapy.
Hilberink JR, Morsink LM, van der Velden WJFM, Mulder AB, Hazenberg CLE, de Groot M, Choi G, Schuringa JJ, Meijer K, Blijlevens NMA, Ammatuna E, Huls G. Hilberink JR, et al. Among authors: schuringa jj. Transplant Cell Ther. 2021 Mar;27(3):246-252. doi: 10.1016/j.jtct.2020.12.014. Epub 2020 Dec 17. Transplant Cell Ther. 2021. PMID: 33781523 Free article.
MLL5 improves ATRA driven differentiation and promotes xenotransplant engraftment in acute promyelocytic leukemia model.
Pereira-Martins DA, Weinhäuser I, Coelho-Silva JL, França-Neto PL, Almeida LY, Bianco TM, Silva CL, França RF, Traina F, Rego EM, Schuringa JJ, Lucena-Araujo AR. Pereira-Martins DA, et al. Among authors: schuringa jj. Cell Death Dis. 2021 Apr 6;12(4):371. doi: 10.1038/s41419-021-03604-z. Cell Death Dis. 2021. PMID: 33824267 Free PMC article.
The Expression of NTAL and Its Protein Interactors Is Associated With Clinical Outcomes in Acute Myeloid Leukemia.
Thomé CH, Ferreira GA, Pereira-Martins DA, Augusto Dos Santos G, Almeida-Silveira DR, Weinhäuser I, Antônio de Souza G, Houtsma R, Schuringa JJ, Rego EM, Faça VM. Thomé CH, et al. Among authors: schuringa jj. Mol Cell Proteomics. 2021;20:100091. doi: 10.1016/j.mcpro.2021.100091. Epub 2021 May 7. Mol Cell Proteomics. 2021. PMID: 33971369 Free PMC article.
The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells.
de Almeida LY, Pereira-Martins DA, Weinhäuser I, Ortiz C, Cândido LA, Lange AP, De Abreu NF, Mendonza SES, de Deus Wagatsuma VM, Do Nascimento MC, Paiva HH, Alves-Paiva RM, Bonaldo CCOM, Nascimento DC, Alves-Filho JC, Scheucher PS, Lima ASG, Schuringa JJ, Ammantuna E, Ottone T, Noguera NI, Araujo CL, Rego EM. de Almeida LY, et al. Among authors: schuringa jj. Front Oncol. 2021 Sep 28;11:686445. doi: 10.3389/fonc.2021.686445. eCollection 2021. Front Oncol. 2021. PMID: 34650910 Free PMC article.
The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia.
Erdem A, Marin S, Pereira-Martins DA, Cortés R, Cunningham A, Pruis MG, de Boer B, van den Heuvel FAJ, Geugien M, Wierenga ATJ, Brouwers-Vos AZ, Rego EM, Huls G, Cascante M, Schuringa JJ. Erdem A, et al. Among authors: schuringa jj. Nat Commun. 2022 Mar 1;13(1):1105. doi: 10.1038/s41467-022-28737-3. Nat Commun. 2022. PMID: 35232995 Free PMC article.
147 results