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ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs.
Lee IT, Nakayama T, Wu CT, Goltsev Y, Jiang S, Gall PA, Liao CK, Shih LC, Schürch CM, McIlwain DR, Chu P, Borchard NA, Zarabanda D, Dholakia SS, Yang A, Kim D, Chen H, Kanie T, Lin CD, Tsai MH, Phillips KM, Kim R, Overdevest JB, Tyler MA, Yan CH, Lin CF, Lin YT, Bau DT, Tsay GJ, Patel ZM, Tsou YA, Tzankov A, Matter MS, Tai CJ, Yeh TH, Hwang PH, Nolan GP, Nayak JV, Jackson PK. Lee IT, et al. Among authors: overdevest jb. Nat Commun. 2020 Oct 28;11(1):5453. doi: 10.1038/s41467-020-19145-6. Nat Commun. 2020. PMID: 33116139 Free PMC article.
Subjective versus Psychophysical Measures of Chemosensory Alterations following COVID-19.
Vilarello BJ, Jacobson PT, Snyder CJ, Choo TH, Gallagher LW, Caruana FF, Tervo JP, Gary JB, Saak TM, Gudis DA, Joseph PV, Goldberg TE, Devanand DP, Overdevest JB. Vilarello BJ, et al. Among authors: overdevest jb. ORL J Otorhinolaryngol Relat Spec. 2024;86(3-4):107-117. doi: 10.1159/000539378. Epub 2024 May 24. ORL J Otorhinolaryngol Relat Spec. 2024. PMID: 38797162 Free article.
Robust ACE2 protein expression localizes to the motile cilia of the respiratory tract epithelia and is not increased by ACE inhibitors or angiotensin receptor blockers.
Lee IT, Nakayama T, Wu CT, Goltsev Y, Jiang S, Gall PA, Liao CK, Shih LC, Schürch CM, McIlwain DR, Chu P, Borchard NA, Zarabanda D, Dholakia SS, Yang A, Kim D, Kanie T, Lin CD, Tsai MH, Phillips KM, Kim R, Overdevest JB, Tyler MA, Yan CH, Lin CF, Lin YT, Bau DT, Tsay GJ, Patel ZM, Tsou YA, Tai CJ, Yeh TH, Hwang PH, Nolan GP, Nayak JV, Jackson PK. Lee IT, et al. Among authors: overdevest jb. medRxiv [Preprint]. 2020 May 12:2020.05.08.20092866. doi: 10.1101/2020.05.08.20092866. medRxiv. 2020. Update in: Nat Commun. 2020 Oct 28;11(1):5453. doi: 10.1038/s41467-020-19145-6 PMID: 32511516 Free PMC article. Updated. Preprint.
Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers.
Nakayama T, Lee IT, Jiang S, Matter MS, Yan CH, Overdevest JB, Wu CT, Goltsev Y, Shih LC, Liao CK, Zhu B, Bai Y, Lidsky P, Xiao Y, Zarabanda D, Yang A, Easwaran M, Schürch CM, Chu P, Chen H, Stalder AK, McIlwain DR, Borchard NA, Gall PA, Dholakia SS, Le W, Xu L, Tai CJ, Yeh TH, Erickson-Direnzo E, Duran JM, Mertz KD, Hwang PH, Haslbauer JD, Jackson PK, Menter T, Andino R, Canoll PD, DeConde AS, Patel ZM, Tzankov A, Nolan GP, Nayak JV. Nakayama T, et al. Among authors: overdevest jb. Cell Rep Med. 2021 Oct 19;2(10):100421. doi: 10.1016/j.xcrm.2021.100421. Epub 2021 Sep 28. Cell Rep Med. 2021. PMID: 34604819 Free PMC article.
89 results