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A protein tertiary structure mimetic modulator of the Hippo signalling pathway.
Adihou H, Gopalakrishnan R, Förster T, Guéret SM, Gasper R, Geschwindner S, Carrillo García C, Karatas H, Pobbati AV, Vazquez-Chantada M, Davey P, Wassvik CM, Pang JKS, Soh BS, Hong W, Chiarparin E, Schade D, Plowright AT, Valeur E, Lemurell M, Grossmann TN, Waldmann H. Adihou H, et al. Among authors: grossmann tn. Nat Commun. 2020 Oct 27;11(1):5425. doi: 10.1038/s41467-020-19224-8. Nat Commun. 2020. PMID: 33110077 Free PMC article.
Direct targeting of Rab-GTPase-effector interactions.
Spiegel J, Cromm PM, Itzen A, Goody RS, Grossmann TN, Waldmann H. Spiegel J, et al. Among authors: grossmann tn. Angew Chem Int Ed Engl. 2014 Feb 24;53(9):2498-503. doi: 10.1002/anie.201308568. Epub 2014 Jan 31. Angew Chem Int Ed Engl. 2014. PMID: 24481744
Small-molecule modulation of Ras signaling.
Spiegel J, Cromm PM, Zimmermann G, Grossmann TN, Waldmann H. Spiegel J, et al. Among authors: grossmann tn. Nat Chem Biol. 2014 Aug;10(8):613-22. doi: 10.1038/nchembio.1560. Epub 2014 Jun 15. Nat Chem Biol. 2014. PMID: 24929527 Review.
Direct Modulation of Small GTPase Activity and Function.
Cromm PM, Spiegel J, Grossmann TN, Waldmann H. Cromm PM, et al. Among authors: grossmann tn. Angew Chem Int Ed Engl. 2015 Nov 9;54(46):13516-37. doi: 10.1002/anie.201504357. Epub 2015 Oct 16. Angew Chem Int Ed Engl. 2015. PMID: 26470842 Review.
New Modalities for Challenging Targets in Drug Discovery.
Valeur E, Guéret SM, Adihou H, Gopalakrishnan R, Lemurell M, Waldmann H, Grossmann TN, Plowright AT. Valeur E, et al. Among authors: grossmann tn. Angew Chem Int Ed Engl. 2017 Aug 21;56(35):10294-10323. doi: 10.1002/anie.201611914. Epub 2017 Jul 24. Angew Chem Int Ed Engl. 2017. PMID: 28186380 Review.
Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119.
Cromm PM, Adihou H, Kapoor S, Vazquez-Chantada M, Davey P, Longmire D, Hennes E, Hofer W, Küchler P, Chiarparin E, Waldmann H, Grossmann TN. Cromm PM, et al. Among authors: grossmann tn. Chembiochem. 2019 Dec 13;20(24):2987-2990. doi: 10.1002/cbic.201900615. Epub 2019 Nov 19. Chembiochem. 2019. PMID: 31680402 Free PMC article.
81 results