Wang L - Search Results

1

Design, synthesis and bioevaluation of inhibitors targeting HSP90-CDC37 protein-protein interaction based on a hydrophobic core.

Zhang Q, Wu X, Zhou J, Zhang L, Xu X, Zhang L, You Q, Wang L. Zhang Q, et al. Among authors: wang l. Eur J Med Chem. 2021 Jan 15;210:112959. doi: 10.1016/j.ejmech.2020.112959. Epub 2020 Oct 22. Eur J Med Chem. 2021. PMID: 33109397

2

Effective screening strategy using ensembled pharmacophore models combined with cascade docking: application to p53-MDM2 interaction inhibitors.

Xue X, Wei JL, Xu LL, Xi MY, Xu XL, Liu F, Guo XK, Wang L, Zhang XJ, Zhang MY, Lu MC, Sun HP, You QD. Xue X, et al. Among authors: wang l. J Chem Inf Model. 2013 Oct 28;53(10):2715-29. doi: 10.1021/ci400348f. Epub 2013 Oct 7. J Chem Inf Model. 2013. PMID: 24050442

3

NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction.

Zhang C, Wang HJ, Bao QC, Wang L, Guo TK, Chen WL, Xu LL, Zhou HS, Bian JL, Yang YR, Sun HP, Xu XL, You QD. Zhang C, et al. Among authors: wang l, wang hj. Oncotarget. 2016 Nov 8;7(45):73593-73606. doi: 10.18632/oncotarget.12435. Oncotarget. 2016. PMID: 27713154 Free PMC article.

4

SHR-A1403, a novel c-Met antibody-drug conjugate, exerts encouraging anti-tumor activity in c-Met-overexpressing models.

Yang CY, Wang L, Sun X, Tang M, Quan HT, Zhang LS, Lou LG, Gou SH. Yang CY, et al. Among authors: wang l. Acta Pharmacol Sin. 2019 Jul;40(7):971-979. doi: 10.1038/s41401-018-0198-0. Epub 2019 Jan 14. Acta Pharmacol Sin. 2019. PMID: 30643210 Free PMC article.

5

Modulation of protein fate decision by small molecules: targeting molecular chaperone machinery.

Wang L, Xu X, Jiang Z, You Q. Wang L, et al. Acta Pharm Sin B. 2020 Oct;10(10):1904-1925. doi: 10.1016/j.apsb.2020.01.018. Epub 2020 Feb 7. Acta Pharm Sin B. 2020. PMID: 33163343 Free PMC article. Review.

6

Discovery of a covalent inhibitor of heat shock protein 90 with antitumor activity that blocks the co-chaperone binding via C-terminal modification.

Li L, Chen N, Xia D, Xu S, Dai W, Tong Y, Wang L, Jiang Z, You Q, Xu X. Li L, et al. Among authors: wang l. Cell Chem Biol. 2021 Oct 21;28(10):1446-1459.e6. doi: 10.1016/j.chembiol.2021.03.016. Epub 2021 Apr 30. Cell Chem Biol. 2021. PMID: 33932325 Free article.

7

A decade of approved first-in-class small molecule orphan drugs: Achievements, challenges and perspectives.

Gu J, Wu Q, Zhang Q, You Q, Wang L. Gu J, et al. Among authors: wang l. Eur J Med Chem. 2022 Dec 5;243:114742. doi: 10.1016/j.ejmech.2022.114742. Epub 2022 Sep 9. Eur J Med Chem. 2022. PMID: 36155354 Review.

8

Proximity-enabled bioreactivity to generate covalent peptide inhibitors of p53-Mdm4.

Hoppmann C, Wang L. Hoppmann C, et al. Among authors: wang l. Chem Commun (Camb). 2016 Apr 14;52(29):5140-3. doi: 10.1039/c6cc01226d. Epub 2016 Mar 21. Chem Commun (Camb). 2016. PMID: 26996321

9

Covalent peptides and proteins for therapeutics.

Berdan VY, Klauser PC, Wang L. Berdan VY, et al. Among authors: wang l. Bioorg Med Chem. 2021 Jan 1;29:115896. doi: 10.1016/j.bmc.2020.115896. Epub 2020 Nov 26. Bioorg Med Chem. 2021. PMID: 33285408 Review.

10

Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways.

Zhu B, Ren C, Du K, Zhu H, Ai Y, Kang F, Luo Y, Liu W, Wang L, Xu Y, Jiang X, Zhang Y. Zhu B, et al. Among authors: wang l. Biochem Pharmacol. 2019 Dec;170:113642. doi: 10.1016/j.bcp.2019.113642. Epub 2019 Sep 18. Biochem Pharmacol. 2019. PMID: 31541631 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

146,794 results

Search Page

Filters