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Page 1
Mitochondrial pyruvate carriers are required for myocardial stress adaptation.
Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED. Zhang Y, et al. Among authors: pewa ad. Nat Metab. 2020 Nov;2(11):1248-1264. doi: 10.1038/s42255-020-00288-1. Epub 2020 Oct 26. Nat Metab. 2020. PMID: 33106689 Free PMC article.
Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis.
Gray LR, Sultana MR, Rauckhorst AJ, Oonthonpan L, Tompkins SC, Sharma A, Fu X, Miao R, Pewa AD, Brown KS, Lane EE, Dohlman A, Zepeda-Orozco D, Xie J, Rutter J, Norris AW, Cox JE, Burgess SC, Potthoff MJ, Taylor EB. Gray LR, et al. Among authors: pewa ad. Cell Metab. 2015 Oct 6;22(4):669-81. doi: 10.1016/j.cmet.2015.07.027. Epub 2015 Sep 3. Cell Metab. 2015. PMID: 26344103 Free PMC article.
Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness.
Sharma A, Oonthonpan L, Sheldon RD, Rauckhorst AJ, Zhu Z, Tompkins SC, Cho K, Grzesik WJ, Gray LR, Scerbo DA, Pewa AD, Cushing EM, Dyle MC, Cox JE, Adams C, Davies BS, Shields RK, Norris AW, Patti G, Zingman LV, Taylor EB. Sharma A, et al. Among authors: pewa ad. Elife. 2019 Jul 18;8:e45873. doi: 10.7554/eLife.45873. Elife. 2019. PMID: 31305240 Free PMC article.
Publisher Correction: Mitochondrial pyruvate carriers are required for myocardial stress adaptation.
Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED. Zhang Y, et al. Among authors: pewa ad. Nat Metab. 2020 Dec;2(12):1498. doi: 10.1038/s42255-020-00322-2. Nat Metab. 2020. PMID: 33208925 No abstract available.
Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis.
Tompkins SC, Sheldon RD, Rauckhorst AJ, Noterman MF, Solst SR, Buchanan JL, Mapuskar KA, Pewa AD, Gray LR, Oonthonpan L, Sharma A, Scerbo DA, Dupuy AJ, Spitz DR, Taylor EB. Tompkins SC, et al. Among authors: pewa ad. Cell Rep. 2019 Sep 3;28(10):2608-2619.e6. doi: 10.1016/j.celrep.2019.07.098. Cell Rep. 2019. PMID: 31484072 Free PMC article.