Liang G - Search Results

1

Identification of a degradation signal at the carboxy terminus of SREBP2: A new role for this domain in cholesterol homeostasis.

Kober DL, Xu S, Li S, Bajaj B, Liang G, Rosenbaum DM, Radhakrishnan A. Kober DL, et al. Among authors: liang g. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28080-28091. doi: 10.1073/pnas.2018578117. Epub 2020 Oct 26. Proc Natl Acad Sci U S A. 2020. PMID: 33106423 Free PMC article.

2

Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis.

Yabe D, Komuro R, Liang G, Goldstein JL, Brown MS. Yabe D, et al. Among authors: liang g. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3155-60. doi: 10.1073/pnas.0130116100. Epub 2003 Mar 6. Proc Natl Acad Sci U S A. 2003. PMID: 12624180 Free PMC article.

3

Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis.

Engelking LJ, Kuriyama H, Hammer RE, Horton JD, Brown MS, Goldstein JL, Liang G. Engelking LJ, et al. Among authors: liang g. J Clin Invest. 2004 Apr;113(8):1168-75. doi: 10.1172/JCI20978. J Clin Invest. 2004. PMID: 15085196 Free PMC article.

4

Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis.

Iizuka K, Bruick RK, Liang G, Horton JD, Uyeda K. Iizuka K, et al. Among authors: liang g. Proc Natl Acad Sci U S A. 2004 May 11;101(19):7281-6. doi: 10.1073/pnas.0401516101. Epub 2004 Apr 26. Proc Natl Acad Sci U S A. 2004. PMID: 15118080 Free PMC article.

5

Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.

Chen G, Liang G, Ou J, Goldstein JL, Brown MS. Chen G, et al. Among authors: liang g. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11245-50. doi: 10.1073/pnas.0404297101. Epub 2004 Jul 20. Proc Natl Acad Sci U S A. 2004. PMID: 15266058 Free PMC article.

6

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.

Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS. Engelking LJ, et al. Among authors: liang g. J Clin Invest. 2005 Sep;115(9):2489-98. doi: 10.1172/JCI25614. Epub 2005 Aug 11. J Clin Invest. 2005. PMID: 16100574 Free PMC article.

7

Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice.

Zhao TJ, Liang G, Li RL, Xie X, Sleeman MW, Murphy AJ, Valenzuela DM, Yancopoulos GD, Goldstein JL, Brown MS. Zhao TJ, et al. Among authors: liang g. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7467-72. doi: 10.1073/pnas.1002271107. Epub 2010 Mar 15. Proc Natl Acad Sci U S A. 2010. PMID: 20231469 Free PMC article.

8

Amino acid substitution in NPC1 that abolishes cholesterol binding reproduces phenotype of complete NPC1 deficiency in mice.

Xie X, Brown MS, Shelton JM, Richardson JA, Goldstein JL, Liang G. Xie X, et al. Among authors: liang g. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15330-5. doi: 10.1073/pnas.1112751108. Epub 2011 Sep 6. Proc Natl Acad Sci U S A. 2011. PMID: 21896731 Free PMC article.

9

The Scap/SREBP pathway is essential for developing diabetic fatty liver and carbohydrate-induced hypertriglyceridemia in animals.

Moon YA, Liang G, Xie X, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Brown MS, Goldstein JL, Horton JD. Moon YA, et al. Among authors: liang g. Cell Metab. 2012 Feb 8;15(2):240-6. doi: 10.1016/j.cmet.2011.12.017. Cell Metab. 2012. PMID: 22326225 Free PMC article.

10

Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes.

Engelking LJ, McFarlane MR, Li CK, Liang G. Engelking LJ, et al. Among authors: liang g. J Lipid Res. 2012 Jul;53(7):1359-68. doi: 10.1194/jlr.M027599. Epub 2012 Apr 22. J Lipid Res. 2012. PMID: 22523394 Free PMC article.

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