Berezovska O - Search Results

1

A Novel NIR-FRET Biosensor for Reporting PS/γ-Secretase Activity in Live Cells.

Houser MC, Hou SS, Perrin F, Turchyna Y, Bacskai BJ, Berezovska O, Maesako M. Houser MC, et al. Among authors: berezovska o. Sensors (Basel). 2020 Oct 22;20(21):5980. doi: 10.3390/s20215980. Sensors (Basel). 2020. PMID: 33105735 Free PMC article.

2

Rapid Notch1 nuclear translocation after ligand binding depends on presenilin-associated gamma-secretase activity.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Ann N Y Acad Sci. 2000;920:223-6. doi: 10.1111/j.1749-6632.2000.tb06926.x. Ann N Y Acad Sci. 2000. PMID: 11193154

3

Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging.

Berezovska O, Ramdya P, Skoch J, Wolfe MS, Bacskai BJ, Hyman BT. Berezovska O, et al. J Neurosci. 2003 Jun 1;23(11):4560-6. doi: 10.1523/JNEUROSCI.23-11-04560.2003. J Neurosci. 2003. PMID: 12805296 Free PMC article.

4

Monitoring proteins in intact cells.

Berezovska O, Bacskai BJ, Hyman BT. Berezovska O, et al. Sci Aging Knowledge Environ. 2003 Jun 11;2003(23):PE14. doi: 10.1126/sageke.2003.23.pe14. Sci Aging Knowledge Environ. 2003. PMID: 12844526

5

Activated Notch1 associates with a presenilin-1/gamma-secretase docking site.

Ramdya P, Skoch J, Bacskai BJ, Hyman BT, Berezovska O. Ramdya P, et al. Among authors: berezovska o. J Neurochem. 2003 Nov;87(4):843-50. doi: 10.1046/j.1471-4159.2003.02030.x. J Neurochem. 2003. PMID: 14622115 Free article.

6

Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation.

Lleó A, Berezovska O, Herl L, Raju S, Deng A, Bacskai BJ, Frosch MP, Irizarry M, Hyman BT. Lleó A, et al. Among authors: berezovska o. Nat Med. 2004 Oct;10(10):1065-6. doi: 10.1038/nm1112. Epub 2004 Sep 26. Nat Med. 2004. PMID: 15448688

7

Familial Alzheimer's disease presenilin 1 mutations cause alterations in the conformation of presenilin and interactions with amyloid precursor protein.

Berezovska O, Lleo A, Herl LD, Frosch MP, Stern EA, Bacskai BJ, Hyman BT. Berezovska O, et al. J Neurosci. 2005 Mar 16;25(11):3009-17. doi: 10.1523/JNEUROSCI.0364-05.2005. J Neurosci. 2005. PMID: 15772361 Free PMC article.

8

Time-domain fluorescent plate reader for cell based protein-protein interaction and protein conformation assays.

Jones PB, Herl L, Berezovska O, Kumar AT, Bacskai BJ, Hyman BT. Jones PB, et al. Among authors: berezovska o. J Biomed Opt. 2006 Sep-Oct;11(5):054024. doi: 10.1117/1.2363367. J Biomed Opt. 2006. PMID: 17092173 Free article.

9

Mutations in amyloid precursor protein affect its interactions with presenilin/gamma-secretase.

Herl L, Thomas AV, Lill CM, Banks M, Deng A, Jones PB, Spoelgen R, Hyman BT, Berezovska O. Herl L, et al. Among authors: berezovska o. Mol Cell Neurosci. 2009 Jun;41(2):166-74. doi: 10.1016/j.mcn.2009.02.008. Epub 2009 Mar 9. Mol Cell Neurosci. 2009. PMID: 19281847 Free PMC article.

10

Allosteric modulation of PS1/gamma-secretase conformation correlates with amyloid beta(42/40) ratio.

Uemura K, Lill CM, Li X, Peters JA, Ivanov A, Fan Z, DeStrooper B, Bacskai BJ, Hyman BT, Berezovska O. Uemura K, et al. Among authors: berezovska o. PLoS One. 2009 Nov 18;4(11):e7893. doi: 10.1371/journal.pone.0007893. PLoS One. 2009. PMID: 19924286 Free PMC article.

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