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Page 1
The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.
Huang J, Lam H, Koziol-White C, Limjunyawong N, Kim D, Kim N, Karmacharya N, Rajkumar P, Firer D, Dalesio NM, Jude J, Kurten RC, Pluznick JL, Deshpande DA, Penn RB, Liggett SB, Panettieri RA Jr, Dong X, An SS. Huang J, et al. Among authors: rajkumar p. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28485-28495. doi: 10.1073/pnas.2003111117. Epub 2020 Oct 23. Proc Natl Acad Sci U S A. 2020. PMID: 33097666 Free PMC article.
Defining an olfactory receptor function in airway smooth muscle cells.
Aisenberg WH, Huang J, Zhu W, Rajkumar P, Cruz R, Santhanam L, Natarajan N, Yong HM, De Santiago B, Oh JJ, Yoon AR, Panettieri RA, Homann O, Sullivan JK, Liggett SB, Pluznick JL, An SS. Aisenberg WH, et al. Among authors: rajkumar p. Sci Rep. 2016 Dec 1;6:38231. doi: 10.1038/srep38231. Sci Rep. 2016. PMID: 27905542 Free PMC article.
Characterizing novel olfactory receptors expressed in the murine renal cortex.
Halperin Kuhns VL, Sanchez J, Sarver DC, Khalil Z, Rajkumar P, Marr KA, Pluznick JL. Halperin Kuhns VL, et al. Among authors: rajkumar p. Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F172-F186. doi: 10.1152/ajprenal.00624.2018. Epub 2019 May 1. Am J Physiol Renal Physiol. 2019. PMID: 31042061 Free PMC article.
Identifying the localization and exploring a functional role for Gprc5c in the kidney.
Rajkumar P, Cha B, Yin J, Arend LJ, Păunescu TG, Hirabayashi Y, Donowitz M, Pluznick JL. Rajkumar P, et al. FASEB J. 2018 Apr;32(4):2046-2059. doi: 10.1096/fj.201700610RR. Epub 2018 Jan 5. FASEB J. 2018. PMID: 29196502 Free PMC article.
Together, these data imply that Gprc5c modulates the renal contribution to systemic pH homeostasis, at least in part, by taking part in the regulation of NHE3.-Rajkumar, P., Cha, B., Yin, J., Arend, L. J., Paunescu, T. G., Hirabayashi, Y., Donowitz, M., Pluznick, J. …
Together, these data imply that Gprc5c modulates the renal contribution to systemic pH homeostasis, at least in part, by taking part in the …
A vicious cycle of frailty and acute lower respiratory infection among community-dwelling adults (≥ 60 years): Findings from a multi-site INSPIRE cohort study, India.
Saha S, Amarchand R, Kumar R, O Prabhakaran A, Rajkumar P, Dutt Bhardwaj S, Kanungo S, Gharpure R, Lafond KE, Azziz-Baumgartner E, Krishnan A. Saha S, et al. Among authors: rajkumar p. PLOS Glob Public Health. 2024 Dec 31;4(12):e0003903. doi: 10.1371/journal.pgph.0003903. eCollection 2024. PLOS Glob Public Health. 2024. PMID: 39739924 Free PMC article.
The microbiome diversifies N-acyl lipid pools - including short-chain fatty acid-derived compounds.
Mannochio-Russo H, Charron-Lamoureux V, van Faassen M, Lamichhane S, Nunes WDG, Deleray V, Patan A, Vittali K, Rajkumar P, El Abiead Y, Zhao HN, Gomes PWP, Mohanty I, Lee C, Sund A, Sharma M, Liu Y, Pattynama D, Walker GT, Norton GJ, Khatib L, Andalibi MS, Wang CX, Ellis RJ, Moore DJ, Iudicello JE, Franklin D Jr, Letendre S, Chin L, Walker C, Renwick S, Zemlin J, Meehan MJ, Song X, Kasper D, Burcham Z, Kim JJ, Kadakia S, Raffatellu M, Bode L, Zengler K, Wang M, Siegel D, Knight R, Dorrestein PC. Mannochio-Russo H, et al. Among authors: rajkumar p. bioRxiv [Preprint]. 2024 Nov 2:2024.10.31.621412. doi: 10.1101/2024.10.31.621412. bioRxiv. 2024. PMID: 39554097 Free PMC article. Preprint.
Empirically establishing drug exposure records directly from untargeted metabolomics data.
Zhao HN, Kvitne KE, Brungs C, Mohan S, Charron-Lamoureux V, Bittremieux W, Tang R, Schmid R, Lamichhane S, El Abiead Y, Andalibi MS, Mannochio-Russo H, Ambre M, Avalon NE, Bryant M, Caraballo-Rodríguez AM, Maya MC, Chin L, Ellis RJ, Franklin D, Girod S, Gomes PWP, Hansen L, Heaton R, Iudicello JE, Jarmusch AK, Khatib L, Letendre S, Magyari S, McDonald D, Mohanty I, Cumsille A, Moore DJ, Rajkumar P, Ross DH, Sapre H, Shahneh MRZ, Thomas SP, Tribelhorn C, Tubb HM, Walker C, Wang CX, Xing S, Zemlin J, Zuffa S, Wishart DS, Kaddurah-Daouk R, Wang M, Raffatellu M, Zengler K, Pluskal T, Xu L, Knight R, Tsunoda SM, Dorrestein PC. Zhao HN, et al. Among authors: rajkumar p. bioRxiv [Preprint]. 2024 Oct 26:2024.10.07.617109. doi: 10.1101/2024.10.07.617109. bioRxiv. 2024. PMID: 39416075 Free PMC article. Preprint.
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