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Spirofused tetrahydroisoquinoline-oxindole hybrids as a novel class of fast acting antimalarial agents with multiple modes of action.
Sci Rep. 2020 Oct 21;10(1):17932. doi: 10.1038/s41598-020-74824-0.
Sci Rep. 2020.
PMID: 33087791
Free PMC article.
In vitro and in vivo studies on anti-malarial activity of Commiphora africana and Dichrostachys cinerea used by the Maasai in Arusha region, Tanzania.
Kweyamba PA, Zofou D, Efange N, Assob JN, Kitau J, Nyindo M.
Kweyamba PA, et al.
Malar J. 2019 Apr 4;18(1):119. doi: 10.1186/s12936-019-2752-8.
Malar J. 2019.
PMID: 30947717
Free PMC article.
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Constituents of the Stem Bark of Trichilia monadelpha (Thonn.) J. J. De Wilde (Meliaceae) and Their Antibacterial and Antiplasmodial Activities.
Djoumessi AK, Nono RN, Neumann B, Stammler HG, Bitchagno GTM, Efange NM, Nkenfou CN, Ayong L, Lenta BN, Sewald N, Nkeng-Efouet-Alango P, Chouna JR.
Djoumessi AK, et al. Among authors: efange nm.
Metabolites. 2023 Feb 17;13(2):298. doi: 10.3390/metabo13020298.
Metabolites. 2023.
PMID: 36837917
Free PMC article.
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Spirofused Tetrahydroisoquinoline-Oxindole Hybrids (Spiroquindolones) as Potential Multitarget Antimalarial Agents: Preliminary Hit Optimization and Efficacy Evaluation in Mice.
Efange NM, Lobe MMM, Yamthe LRT, Pekam JNM, Tarkang PA, Ayong L, Efange SMN.
Efange NM, et al.
Antimicrob Agents Chemother. 2022 Dec 20;66(12):e0060722. doi: 10.1128/aac.00607-22. Epub 2022 Nov 21.
Antimicrob Agents Chemother. 2022.
PMID: 36409128
Free PMC article.
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