Spitz DR - Search Results

1

Glutaminase Inhibitors Induce Thiol-Mediated Oxidative Stress and Radiosensitization in Treatment-Resistant Cervical Cancers.

Rashmi R, Jayachandran K, Zhang J, Menon V, Muhammad N, Zahner M, Ruiz F, Zhang S, Cho K, Wang Y, Huang X, Huang Y, McCormick ML, Rogers BE, Spitz DR, Patti GJ, Schwarz JK. Rashmi R, et al. Among authors: spitz dr. Mol Cancer Ther. 2020 Dec;19(12):2465-2475. doi: 10.1158/1535-7163.MCT-20-0271. Epub 2020 Oct 21. Mol Cancer Ther. 2020. PMID: 33087507 Free PMC article.

2

Relationship between changes in ploidy and stable cellular resistance to hydrogen peroxide.

Spitz DR, Mackey MA, Li GC, Elwell JH, McCormick ML, Oberley LW. Spitz DR, et al. J Cell Physiol. 1989 Jun;139(3):592-8. doi: 10.1002/jcp.1041390320. J Cell Physiol. 1989. PMID: 2738104

3

The isolation and partial characterization of stable H2O2-resistant variants of Chinese hamster fibroblasts.

Spitz DR, Li GC, McCormick ML, Sun Y, Oberley LW. Spitz DR, et al. Basic Life Sci. 1988;49:549-52. doi: 10.1007/978-1-4684-5568-7_86. Basic Life Sci. 1988. PMID: 3250510 No abstract available.

4

Stable H2O2-resistant variants of Chinese hamster fibroblasts demonstrate increases in catalase activity.

Spitz DR, Li GC, McCormick ML, Sun Y, Oberley LW. Spitz DR, et al. Radiat Res. 1988 Apr;114(1):114-24. Radiat Res. 1988. PMID: 3353499

5

Genomic instability and catalase gene amplification induced by chronic exposure to oxidative stress.

Hunt CR, Sim JE, Sullivan SJ, Featherstone T, Golden W, Von Kapp-Herr C, Hock RA, Gomez RA, Parsian AJ, Spitz DR. Hunt CR, et al. Among authors: spitz dr. Cancer Res. 1998 Sep 1;58(17):3986-92. Cancer Res. 1998. PMID: 9731512

6

Increased activator protein 1 activity as well as resistance to heat-induced radiosensitization, hydrogen peroxide, and cisplatin are inhibited by indomethacin in oxidative stress-resistant cells.

Bradbury CM, Locke JE, Wei SJ, Rene LM, Karimpour S, Hunt C, Spitz DR, Gius D. Bradbury CM, et al. Among authors: spitz dr. Cancer Res. 2001 Apr 15;61(8):3486-92. Cancer Res. 2001. PMID: 11309312

7

2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism.

Lin X, Zhang F, Bradbury CM, Kaushal A, Li L, Spitz DR, Aft RL, Gius D. Lin X, et al. Among authors: spitz dr. Cancer Res. 2003 Jun 15;63(12):3413-7. Cancer Res. 2003. PMID: 12810678

8

Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co-expressing HCV core protein and CYP2E1.

Wen F, Abdalla MY, Aloman C, Xiang J, Ahmad IM, Walewski J, McCormick ML, Brown KE, Branch AD, Spitz DR, Britigan BE, Schmidt WN. Wen F, et al. Among authors: spitz dr. J Med Virol. 2004 Feb;72(2):230-40. doi: 10.1002/jmv.10567. J Med Virol. 2004. PMID: 14695664

9

Treatment of pancreatic cancer cells with dicumarol induces cytotoxicity and oxidative stress.

Lewis A, Ough M, Li L, Hinkhouse MM, Ritchie JM, Spitz DR, Cullen JJ. Lewis A, et al. Among authors: spitz dr. Clin Cancer Res. 2004 Jul 1;10(13):4550-8. doi: 10.1158/1078-0432.CCR-03-0667. Clin Cancer Res. 2004. PMID: 15240547

10

Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicity of 2-deoxy-D-glucose.

Andringa KK, Coleman MC, Aykin-Burns N, Hitchler MJ, Walsh SA, Domann FE, Spitz DR. Andringa KK, et al. Among authors: spitz dr. Cancer Res. 2006 Feb 1;66(3):1605-10. doi: 10.1158/0008-5472.CAN-05-3462. Cancer Res. 2006. PMID: 16452219

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