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Opsonized antigen activates Vδ2+ T cells via CD16/FCγRIIIa in individuals with chronic malaria exposure.
Farrington LA, Callaway PC, Vance HM, Baskevitch K, Lutz E, Warrier L, McIntyre TI, Budker R, Jagannathan P, Nankya F, Musinguzi K, Nalubega M, Sikyomu E, Naluwu K, Arinaitwe E, Dorsey G, Kamya MR, Feeney ME. Farrington LA, et al. PLoS Pathog. 2020 Oct 21;16(10):e1008997. doi: 10.1371/journal.ppat.1008997. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33085728 Free PMC article.
Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations.
Boyle MJ, Jagannathan P, Bowen K, McIntyre TI, Vance HM, Farrington LA, Greenhouse B, Nankya F, Rek J, Katureebe A, Arinaitwe E, Dorsey G, Kamya MR, Feeney ME. Boyle MJ, et al. Among authors: farrington la. J Infect Dis. 2015 Aug 1;212(3):416-25. doi: 10.1093/infdis/jiv054. Epub 2015 Feb 2. J Infect Dis. 2015. PMID: 25646355 Free PMC article.
Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria.
Boyle MJ, Jagannathan P, Farrington LA, Eccles-James I, Wamala S, McIntyre TI, Vance HM, Bowen K, Nankya F, Auma A, Nalubega M, Sikyomu E, Naluwu K, Rek J, Katureebe A, Bigira V, Kapisi J, Tappero J, Muhindo MK, Greenhouse B, Arinaitwe E, Dorsey G, Kamya MR, Feeney ME. Boyle MJ, et al. Among authors: farrington la. PLoS Pathog. 2015 Jul 16;11(7):e1005041. doi: 10.1371/journal.ppat.1005041. eCollection 2015 Jul. PLoS Pathog. 2015. PMID: 26182204 Free PMC article.
Frequent Malaria Drives Progressive Vδ2 T-Cell Loss, Dysfunction, and CD16 Up-regulation During Early Childhood.
Farrington LA, Jagannathan P, McIntyre TI, Vance HM, Bowen K, Boyle MJ, Nankya F, Wamala S, Auma A, Nalubega M, Sikyomu E, Naluwu K, Bigira V, Kapisi J, Dorsey G, Kamya MR, Feeney ME. Farrington LA, et al. J Infect Dis. 2016 May 1;213(9):1483-90. doi: 10.1093/infdis/jiv600. Epub 2015 Dec 13. J Infect Dis. 2016. PMID: 26667315 Free PMC article. Clinical Trial.
Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure.
Jagannathan P, Lutwama F, Boyle MJ, Nankya F, Farrington LA, McIntyre TI, Bowen K, Naluwu K, Nalubega M, Musinguzi K, Sikyomu E, Budker R, Katureebe A, Rek J, Greenhouse B, Dorsey G, Kamya MR, Feeney ME. Jagannathan P, et al. Among authors: farrington la. Sci Rep. 2017 Sep 13;7(1):11487. doi: 10.1038/s41598-017-10624-3. Sci Rep. 2017. PMID: 28904345 Free PMC article.
Effective Antimalarial Chemoprevention in Childhood Enhances the Quality of CD4+ T Cells and Limits Their Production of Immunoregulatory Interleukin 10.
Jagannathan P, Bowen K, Nankya F, McIntyre TI, Auma A, Wamala S, Sikyomu E, Naluwu K, Nalubega M, Boyle MJ, Farrington LA, Bigira V, Kapisi J, Aweeka F, Greenhouse B, Kamya M, Dorsey G, Feeney ME. Jagannathan P, et al. Among authors: farrington la. J Infect Dis. 2016 Jul 15;214(2):329-38. doi: 10.1093/infdis/jiw147. Epub 2016 Apr 10. J Infect Dis. 2016. PMID: 27067196 Free PMC article. Clinical Trial.
The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission.
Boyle MJ, Jagannathan P, Bowen K, McIntyre TI, Vance HM, Farrington LA, Schwartz A, Nankya F, Naluwu K, Wamala S, Sikyomu E, Rek J, Greenhouse B, Arinaitwe E, Dorsey G, Kamya MR, Feeney ME. Boyle MJ, et al. Among authors: farrington la. Front Immunol. 2017 Oct 19;8:1329. doi: 10.3389/fimmu.2017.01329. eCollection 2017. Front Immunol. 2017. PMID: 29097996 Free PMC article.
25 results