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IgM autoantibodies recognizing ACE2 are associated with severe COVID-19.
Casciola-Rosen L, Thiemann DR, Andrade F, Trejo Zambrano MI, Hooper JE, Leonard EK, Spangler JB, Cox AL, Machamer CE, Sauer L, Laeyendecker O, Garibaldi BT, Ray SC, Mecoli CA, Christopher-Stine L, Gutierrez-Alamillo L, Yang Q, Hines D, Clarke WA, Rothman R, Pekosz A, Fenstermacher KJ, Wang Z, Zeger SL, Rosen A. Casciola-Rosen L, et al. Among authors: laeyendecker o. medRxiv [Preprint]. 2020 Oct 15:2020.10.13.20211664. doi: 10.1101/2020.10.13.20211664. medRxiv. 2020. Update in: JCI Insight. 2022 May 9;7(9):e158362. doi: 10.1172/jci.insight.158362 PMID: 33083808 Free PMC article. Updated. Preprint.
COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva.
Randad PR, Pisanic N, Kruczynski K, Manabe YC, Thomas D, Pekosz A, Klein SL, Betenbaugh MJ, Clarke WA, Laeyendecker O, Caturegli PP, Larman HB, Detrick B, Fairley JK, Sherman AC, Rouphael N, Edupuganti S, Granger DA, Granger SW, Collins M, Heaney CD. Randad PR, et al. Among authors: laeyendecker o. medRxiv [Preprint]. 2020 May 26:2020.05.24.20112300. doi: 10.1101/2020.05.24.20112300. medRxiv. 2020. Update in: J Clin Microbiol. 2020 Dec 17;59(1):e02204-20. doi: 10.1128/JCM.02204-20 PMID: 32511537 Free PMC article. Updated. Preprint.
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population.
Klein S, Pekosz A, Park HS, Ursin R, Shapiro J, Benner S, Littlefield K, Kumar S, Naik HM, Betenbaugh M, Shrestha R, Wu A, Hughes R, Burgess I, Caturegli P, Laeyendecker O, Quinn T, Sullivan D, Shoham S, Redd A, Bloch E, Casadevall A, Tobian A. Klein S, et al. Among authors: laeyendecker o. medRxiv [Preprint]. 2020 Jun 28:2020.06.26.20139063. doi: 10.1101/2020.06.26.20139063. medRxiv. 2020. Update in: J Clin Invest. 2020 Nov 2;130(11):6141-6150. doi: 10.1172/JCI142004 PMID: 32607519 Free PMC article. Updated. Preprint.
Evaluation of Serological SARS-CoV-2 Lateral Flow Assays for Rapid Point of Care Testing.
Conklin SE, Martin K, Manabe YC, Schmidt HA, Keruly M, Klock E, Kirby CS, Baker OR, Fernandez RE, Eby YJ, Hardick J, Shaw-Saliba K, Rothman RE, Caturegli PP, Redd AR, Tobian AA, Bloch EM, Larman HB, Quinn TC, Clarke W, Laeyendecker O. Conklin SE, et al. Among authors: laeyendecker o. medRxiv [Preprint]. 2020 Aug 4:2020.07.31.20166041. doi: 10.1101/2020.07.31.20166041. medRxiv. 2020. Update in: J Clin Microbiol. 2021 Jan 21;59(2):e02020-20. doi: 10.1128/JCM.02020-20 PMID: 32793916 Free PMC article. Updated. Preprint.
Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers.
Patel EU, Bloch EM, Clarke W, Hsieh YH, Boon D, Eby Y, Fernandez RE, Baker OR, Keruly M, Kirby CS, Klock E, Littlefield K, Miller J, Schmidt HA, Sullivan P, Piwowar-Manning E, Shrestha R, Redd AD, Rothman RE, Sullivan D, Shoham S, Casadevall A, Quinn TC, Pekosz A, Tobian AAR, Laeyendecker O. Patel EU, et al. Among authors: laeyendecker o. medRxiv [Preprint]. 2020 Sep 2:2020.08.31.20184788. doi: 10.1101/2020.08.31.20184788. medRxiv. 2020. Update in: J Clin Microbiol. 2021 Jan 21;59(2):e02257-20. doi: 10.1128/JCM.02257-20 PMID: 32908987 Free PMC article. Updated. Preprint.
SARS-CoV-2 antibody signatures robustly predict diverse antiviral functions relevant for convalescent plasma therapy.
Natarajan H, Crowley AR, Butler SE, Xu S, Weiner JA, Bloch EM, Littlefield K, Wieland-Alter W, Connor RI, Wright PF, Benner SE, Bonny TS, Laeyendecker O, Sullivan D, Shoham S, Quinn TC, Larman HB, Casadevall A, Pekosz A, Redd AD, Tobian AAR, Ackerman ME. Natarajan H, et al. Among authors: laeyendecker o. medRxiv [Preprint]. 2020 Sep 18:2020.09.16.20196154. doi: 10.1101/2020.09.16.20196154. medRxiv. 2020. PMID: 32995801 Free PMC article. Updated. Preprint.
Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality.
Morgenlander W, Henson S, Monaco D, Chen A, Littlefield K, Bloch EM, Fujimura E, Ruczinski I, Crowley AR, Natarajan H, Butler SE, Weiner JA, Li MZ, Bonny TS, Benner SE, Ashwin Balagopal, Sullivan D, Shoham S, Quinn TC, Eshleman S, Casadevall A, Redd AD, Laeyendecker O, Ackerman ME, Pekosz A, Elledge SJ, Robinson M, Tobian AAR, Larman HB. Morgenlander W, et al. Among authors: laeyendecker o. medRxiv [Preprint]. 2020 Dec 18:2020.12.16.20248294. doi: 10.1101/2020.12.16.20248294. medRxiv. 2020. Update in: J Clin Invest. 2021 Apr 1;131(7):146927. doi: 10.1172/JCI146927 PMID: 33354688 Free PMC article. Updated. Preprint.
Comparative performance of multiplex salivary and commercially available serologic assays to detect SARS-CoV-2 IgG and neutralization titers.
Heaney CD, Pisanic N, Randad PR, Kruczynski K, Howard T, Zhu X, Littlefield K, Patel EU, Shrestha R, Laeyendecker O, Shoham S, Sullivan D, Gebo K, Hanley D, Redd AD, Quinn TC, Casadevall A, Zenilman JM, Pekosz A, Bloch EM, Tobian AAR. Heaney CD, et al. Among authors: laeyendecker o. medRxiv [Preprint]. 2021 Feb 1:2021.01.28.21250717. doi: 10.1101/2021.01.28.21250717. medRxiv. 2021. Update in: J Clin Virol. 2021 Dec;145:104997. doi: 10.1016/j.jcv.2021.104997 PMID: 33532806 Free PMC article. Updated. Preprint.
CD8+ T cell responses in COVID-19 convalescent individuals target conserved epitopes from multiple prominent SARS-CoV-2 circulating variants.
Redd AD, Nardin A, Kared H, Bloch EM, Pekosz A, Laeyendecker O, Abel B, Fehlings M, Quinn TC, Tobian AA. Redd AD, et al. Among authors: laeyendecker o. medRxiv [Preprint]. 2021 Feb 12:2021.02.11.21251585. doi: 10.1101/2021.02.11.21251585. medRxiv. 2021. Update in: Open Forum Infect Dis. 2021 Mar 30;8(7):ofab143. doi: 10.1093/ofid/ofab143 PMID: 33594378 Free PMC article. Updated. Preprint.
Differential Performance of CoronaCHEK SARS-CoV-2 Lateral Flow Antibody Assay by Geographic Origin of Samples.
Baker OR, Grabowski MK, Galiwango RM, Nalumansi A, Serwanga J, Clarke W, Hsieh YH, Rothman RE, Fernandez RE, Serwadda D, Kagaayi J, Lutalo T, Reynolds SJ, Kaleebu P, Quinn TC, Laeyendecker O. Baker OR, et al. Among authors: laeyendecker o. medRxiv [Preprint]. 2021 Apr 19:2021.04.12.21255284. doi: 10.1101/2021.04.12.21255284. medRxiv. 2021. Update in: J Clin Microbiol. 2021 Jun 18;59(7):e0083721. doi: 10.1128/JCM.00837-21 PMID: 33880484 Free PMC article. Updated. Preprint.
321 results