Wellems TE - Search Results

1

Regioisomerization of Antimalarial Drug WR99210 Explains the Inactivity of a Commercial Stock.

Remcho TP, Guggilapu SD, Cruz P, Nardone GA, Heffernan G, O'Connor RD, Bewley CA, Wellems TE, Lane KD. Remcho TP, et al. Among authors: wellems te. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01385-20. doi: 10.1128/AAC.01385-20. Print 2020 Dec 16. Antimicrob Agents Chemother. 2020. PMID: 33077647 Free PMC article.

2

PfCG2, a Plasmodium falciparum protein peripherally associated with the parasitophorous vacuolar membrane, is expressed in the period of maximum hemoglobin uptake and digestion by trophozoites.

Cooper RA, Papakrivos J, Lane KD, Fujioka H, Lingelbach K, Wellems TE. Cooper RA, et al. Among authors: wellems te. Mol Biochem Parasitol. 2005 Dec;144(2):167-76. doi: 10.1016/j.molbiopara.2005.07.009. Epub 2005 Sep 7. Mol Biochem Parasitol. 2005. PMID: 16183150

3

Kelch Mutations in Plasmodium falciparum Protein K13 Do Not Modulate Dormancy after Artemisinin Exposure and Sorbitol Selection In Vitro.

Breglio KF, Rahman RS, Sá JM, Hott A, Roberts DJ, Wellems TE. Breglio KF, et al. Among authors: wellems te. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02256-17. doi: 10.1128/AAC.02256-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29463530 Free PMC article.

4

Selection of Plasmodium falciparum cytochrome B mutants by putative PfNDH2 inhibitors.

Lane KD, Mu J, Lu J, Windle ST, Liu A, Sun PD, Wellems TE. Lane KD, et al. Among authors: wellems te. Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6285-6290. doi: 10.1073/pnas.1804492115. Epub 2018 May 29. Proc Natl Acad Sci U S A. 2018. PMID: 29844160 Free PMC article.

5

Correction for Breglio et al., "Kelch Mutations in Plasmodium falciparum Protein K13 Do Not Modulate Dormancy after Artemisinin Exposure and Sorbitol Selection In Vitro".

Breglio KF, Rahman RS, Sá JM, Hott A, Roberts DJ, Wellems TE. Breglio KF, et al. Among authors: wellems te. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e02070-18. doi: 10.1128/AAC.02070-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30355752 Free PMC article. No abstract available.

6

Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution.

Su XZ, Lane KD, Xia L, Sá JM, Wellems TE. Su XZ, et al. Among authors: wellems te. Clin Microbiol Rev. 2019 Jul 31;32(4):e00019-19. doi: 10.1128/CMR.00019-19. Print 2019 Sep 18. Clin Microbiol Rev. 2019. PMID: 31366610 Free PMC article. Review.

7

Evidence for linkage of pfmdr1, pfcrt, and pfk13 polymorphisms to lumefantrine and mefloquine susceptibilities in a Plasmodium falciparum cross.

Windle ST, Lane KD, Gadalla NB, Liu A, Mu J, Caleon RL, Rahman RS, Sá JM, Wellems TE. Windle ST, et al. Among authors: wellems te. Int J Parasitol Drugs Drug Resist. 2020 Dec;14:208-217. doi: 10.1016/j.ijpddr.2020.10.009. Epub 2020 Oct 27. Int J Parasitol Drugs Drug Resist. 2020. PMID: 33197753 Free PMC article.

8

A Plasmodium falciparum RING Finger E3 Ubiquitin Ligase Modifies the Roles of PfMDR1 and PfCRT in Parasite Drug Responses.

Singh BK, Zhang C, Wu J, Peng YC, He X, Tumas KC, Sá JM, Lane KD, Eastman RT, Narum DL, Wellems TE, Su XZ. Singh BK, et al. Among authors: wellems te. Antimicrob Agents Chemother. 2023 Feb 16;67(2):e0082122. doi: 10.1128/aac.00821-22. Epub 2023 Jan 10. Antimicrob Agents Chemother. 2023. PMID: 36625569 Free PMC article.

9

Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine.

Cooper RA, Lane KD, Deng B, Mu J, Patel JJ, Wellems TE, Su X, Ferdig MT. Cooper RA, et al. Among authors: wellems te. Mol Microbiol. 2007 Jan;63(1):270-82. doi: 10.1111/j.1365-2958.2006.05511.x. Epub 2006 Dec 5. Mol Microbiol. 2007. PMID: 17163969 Free article.

10

Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil.

Fidock DA, Wellems TE. Fidock DA, et al. Among authors: wellems te. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10931-6. doi: 10.1073/pnas.94.20.10931. Proc Natl Acad Sci U S A. 1997. PMID: 9380737 Free PMC article.

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